Technische Universität Dresden

Quick facts

Marketed products

• Adapalen · Metabolic
• all-trans retinoid acid
• amine fluoride/stannous fluoride · Dental/Oral Health
  Amine fluoride and stannous fluoride work together to strengthen tooth enamel and inhibit bacterial acid production to prevent dental caries.
• Ciclosporine A
• Cytarabine Dosage
• Cytarabine vs. Cytarabine+Amsacrine+Mitoxantrone · Oncology
  Cytarabine is a cytidine analog that inhibits DNA synthesis, while the combination with amsacrine and mitoxantrone adds topoisomerase II inhibition and intercalating DNA damage to enhance leukemic cell killing.
• Elidel-Creme · Dermatology/Immunology
  Elidel (pimecrolimus) is a calcineurin inhibitor that suppresses T-cell activation and inflammatory cytokine production in the skin.
• Fludarabine (Flud) · Oncology
  Fludarabine is a purine analog that inhibits ribonucleotide reductase and DNA polymerase, leading to disruption of DNA synthesis and cell death in rapidly dividing cells.
• Gilteritinib (GILT) · Oncology
  Gilteritinib is a tyrosine kinase inhibitor that selectively targets FLT3 (FMS-like tyrosine kinase 3) to inhibit proliferation of acute myeloid leukemia cells.
• Midazolam (sedative) · Neurology / Anesthesia
  Midazolam is a benzodiazepine that enhances the inhibitory effects of GABA at GABA-A receptors in the central nervous system, producing sedation and anxiolysis.
• Piritramid (analgetic) · Pain Management
  Piritramid is a synthetic opioid agonist that binds to mu opioid receptors in the central nervous system to produce analgesia.
• randomization between two established Chemotherapies · Oncology
  This is a randomized clinical trial comparing two established chemotherapy regimens rather than a single drug entity.

Phase 3 pipeline

• 5-Azacytidin · Oncology
  5-Azacytidine is a DNA methyltransferase inhibitor that reduces DNA methylation and promotes re-expression of silenced tumor suppressor genes.
• Placebo lead in
  Placebo lead-in is a study design phase where patients receive placebo before randomization to active treatment, used to establish baseline disease progression and identify placebo responders.
• Prophylactic platelet transfusion · Hematology
  Prophylactic platelet transfusion involves administering platelets to prevent bleeding in patients with low platelet counts.
• Therapeutic platelet transfusion · Hematology
  Therapeutic platelet transfusion involves administering platelets to a patient to increase their platelet count and improve blood clotting.

Phase 1 pipeline

• Dermatop · Dermatology
• hydrocortisonacetat 1% cream

Competitive intelligence

For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors:

• Technische Universität Dresden portfolio CI brief
• Technische Universität Dresden pipeline updates RSS