ALK-Abelló A/S

Quick facts

Marketed products

• AIT Tablet · Immunology / Allergy
  AIT Tablet is an allergen immunotherapy tablet that desensitizes the immune system to specific allergens through gradual oral exposure.
• Grazax · Other
• Pangramin Plus D. pteronyssinus 100%

Phase 3 pipeline

• ALK Grass tablet · Immunology / Allergy
  ALK Grass tablet is an allergen immunotherapy that desensitizes the immune system to grass pollen allergens through gradual exposure.
• ALK HDM AIT 12 DU · Immunology / Allergy
  ALK HDM AIT 12 DU is an allergen immunotherapy (AIT) vaccine that desensitizes the immune system to house dust mite (HDM) allergens through repeated subcutaneous administration.
• ALK HDM AIT 6 DU · Immunology / Allergy
  ALK HDM AIT 6 DU is an allergen immunotherapy (AIT) vaccine that desensitizes the immune system to house dust mite (HDM) allergens through repeated subcutaneous administration.
• Grazax + Aerius · Immunology / Allergy
  Grazax is a sublingual immunotherapy tablet that desensitizes the immune system to grass pollen allergens, while Aerius (desloratadine) is an antihistamine that blocks histamine receptors to reduce allergic symptoms.
• Grazax-R · Immunology / Allergy
  Grazax-R is an oral immunotherapy that desensitizes the immune system to grass pollen allergens through gradual exposure under the tongue.
• HDM SLIT-tablet · Immunology / Allergy
  HDM SLIT-tablet is a sublingual immunotherapy that delivers house dust mite allergen extract to induce immune tolerance and reduce allergic responses.
• HDM SLIT-tablet (12 SQ-HDM) · Immunology / Allergy
  HDM SLIT-tablet delivers house dust mite allergen extract sublingually to induce immune tolerance through oral mucosal sensitization.
• MK-8237 tablets · Immunology
  MK-8237 is an oral immunotherapeutic agent designed to modulate immune responses, likely through toll-like receptor (TLR) signaling or related innate immune pathways.
• Olopatadine 0.1% Rescue Treatment · Ophthalmology / Allergy
  Olopatadine is a selective H1-receptor antagonist and mast cell stabilizer that blocks histamine-mediated allergic responses in the eye.
• Pangramin SLIT HDM mix. · Immunology / Allergy
  Pangramin SLIT HDM mix is a sublingual immunotherapy that desensitizes the immune system to house dust mite allergens through repeated exposure to gradually increasing doses.
• Placebo for SCH 39641
  This is a placebo control with no active pharmacological mechanism.
• Placebo for SCH 697243
  Placebos do not have an active pharmacological mechanism; they are used as controls in clinical trials.
• Placebo SLIT-tablet · Immunology
  A placebo sublingual immunotherapy tablet designed to assess efficacy and safety in phase 3 trials by delivering no active therapeutic agent.
• Rescue Medication: Loratadine tablets · Allergy/Immunology
  Loratadine is a selective H1-receptor antagonist that blocks histamine-mediated allergic responses without significant central nervous system penetration.
• Rescue Medication: Olopatadine ophthalmic drops · Ophthalmology / Allergy
  Olopatadine is a selective H1-receptor antagonist and mast cell stabilizer that blocks histamine-mediated allergic responses in the eye.
• Rescue Medication: Self-Injectable Epinephrine · Immunology; Allergy/Anaphylaxis
  Epinephrine is a sympathomimetic amine that binds to alpha and beta adrenergic receptors to rapidly reverse the symptoms of anaphylaxis by increasing blood pressure, improving airway patency, and reducing allergic mediator release.
• SCH 39641 · Immunology / Respiratory
  SCH 39641 is a leukotriene receptor antagonist that blocks cysteinyl leukotriene receptors to reduce inflammatory responses.
• SCH 697243 · Oncology
  SCH 697243 is a toll-like receptor 9 (TLR9) agonist that activates innate immune responses to enhance anti-tumor immunity.
• subcutaneous immunotherapy · Immunology
  Subcutaneous immunotherapy involves administering allergens or allergen extracts under the skin to build tolerance and reduce allergic reactions.
• Sublingual allergy immunotherapy tablet · Immunology
  Sublingual allergy immunotherapy tablets work by exposing the body to small amounts of an allergen to build up tolerance and reduce symptoms.
• Tree SLIT-tablet · Immunology / Allergy
  Tree SLIT-tablet is a sublingual immunotherapy that desensitizes the immune system to tree pollen allergens by gradually exposing patients to increasing doses of allergen extract.

Phase 2 pipeline

• ALK HDM tablet
• ALK tree AIT 0.5 DU
• ALK tree AIT 1 DU · Oncology
  ALK tree AIT 1 DU is a targeted therapy that works by inhibiting the anaplastic lymphoma kinase (ALK) protein.
• ALK tree AIT 12 DU
• ALK tree AIT 2 DU
• ALK tree AIT 4 DU
• ALK tree AIT 7 DU · Oncology
  ALK tree AIT 7 DU is a targeted therapy that works by inhibiting the anaplastic lymphoma kinase (ALK) protein.
• AVANZ Cupressus
• AVANZ MITE
• AVANZ olea
• AVANZ Phleum pratense
• AVANZ Salsola
• MK-8237 12 DU
• MK-8237 6 DU
• Osiris Phleum pratense
• SCH 39641 12 Amb a 1-U
• SCH 39641 6 Amb a 1-U
• SLITone ULTRA HDM immunotherapy
• SQ SLIT-tablet
• SQ tree SLIT-tablet
• Tablet, Dispersible

Phase 1 pipeline

• ALK Ragweed Tablet
• Betula Verrucosa allergen extract
• Peanut SLIT-tablet

Competitive intelligence

For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors:

• ALK-Abelló A/S portfolio CI brief
• ALK-Abelló A/S pipeline updates RSS