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Sublingual allergy immunotherapy tablet
Sublingual allergy immunotherapy tablets work by exposing the body to small amounts of an allergen to build up tolerance and reduce symptoms.
Sublingual allergy immunotherapy tablets work by exposing the body to small amounts of an allergen to build up tolerance and reduce symptoms. Used for Treatment of grass pollen allergy symptoms.
At a glance
| Generic name | Sublingual allergy immunotherapy tablet |
|---|---|
| Also known as | Acarizax, Odactra |
| Sponsor | ALK-Abelló A/S |
| Drug class | Allergen immunotherapy |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
This process, known as desensitization, involves the gradual introduction of increasing amounts of the allergen to the body, allowing the immune system to adapt and reduce its response. Over time, this can lead to a decrease in symptoms such as itching, sneezing, and congestion.
Approved indications
- Treatment of grass pollen allergy symptoms
Common side effects
- Oral itching
- Sore throat
- Swollen tongue
Key clinical trials
- Peanut Sublingual Immunotherapy (SLIT)-Tablet for Treatment of Peanut Allergy (PHASE1, PHASE2)
- Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction (PHASE2)
- Potency of HDM Sublingual AIT Tablets in Assuring the Persistency of Asthma Control in HDM Allergic Patients With Severe Asthma, Treated With Tezepelumab (PHASE3)
- A Study in Children and Adolescents With Birch Pollen-induced Rhinoconjunctivitis (PHASE3)
- House Dust Mite Allergy Trial In Children (PHASE3)
- Evaluate Measurement Instruments Relevance in Assessing Effectiveness of ACARIZAX® in House Dust Mite Allergic Rhinitis
- Mite Asthma Pediatric Immunotherapy Trial (PHASE3)
- Comparative Real World Effectiveness of SQ Sublingual Immunotherapy (SLIT)-Tablets vs. Controls in Allergic Rhinitis and Asthma
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Sublingual allergy immunotherapy tablet CI brief — competitive landscape report
- Sublingual allergy immunotherapy tablet updates RSS · CI watch RSS
- ALK-Abelló A/S portfolio CI