Topical antimicrobial and keratolytic agent

This page covers all Topical antimicrobial and keratolytic agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Bacterial protein synthesis inhibition; mitochondrial oxidative stress in bacteria, Cutibacterium acnes (bacterial target); non-specific oxidative mechanism.

Targets

Bacterial protein synthesis inhibition; mitochondrial oxidative stress in bacteria · Cutibacterium acnes (bacterial target); non-specific oxidative mechanism

Marketed (4)

• Benzoyl Peroxide Topical · University of Missouri-Columbia · Dermatology
  Benzoyl peroxide kills acne-causing bacteria and promotes skin cell turnover by generating reactive oxygen species.
• Benzoyl peroxide 5% gel · University of Southern California · Dermatology
  Benzoyl peroxide kills acne-causing bacteria and promotes skin cell turnover by generating reactive oxygen species.
• ABPO Forte Gel · Galderma R&D · Dermatology
  ABPO Forte Gel is a topical formulation containing azelaic acid that reduces bacterial colonization and normalizes keratinization to treat acne and rosacea.
• BPO · Galderma R&D · Dermatology
  BPO (benzoyl peroxide) kills acne-causing bacteria and reduces sebum production while promoting skin cell turnover.

Phase 3 pipeline (1)

• Benzoyl Peroxide 4 % Topical Cream · Pak Emirates Military Hospital · Dermatology
  Benzoyl peroxide kills acne-causing bacteria and promotes skin cell turnover by generating reactive oxygen species.

Patent intelligence

• topical antimicrobial and keratolytic agent patent landscape — aggregated cliff calendar, attackable patents, originator estates