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Benzoyl Peroxide 4 % Topical Cream
Benzoyl peroxide kills acne-causing bacteria and promotes skin cell turnover by generating reactive oxygen species.
Benzoyl peroxide kills acne-causing bacteria and promotes skin cell turnover by generating reactive oxygen species. Used for Acne vulgaris (mild to moderate), Acne rosacea (adjunctive).
At a glance
| Generic name | Benzoyl Peroxide 4 % Topical Cream |
|---|---|
| Also known as | "Benoxyl" by "Glitz pharma" |
| Sponsor | Pak Emirates Military Hospital |
| Drug class | Topical antimicrobial and keratolytic agent |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | Phase 3 |
Mechanism of action
Benzoyl peroxide is a potent oxidizing agent that penetrates the skin and decomposes to produce benzoic acid and oxygen radicals, which are bactericidal against Cutibacterium acnes (formerly Propionibacterium acnes). It also has keratolytic properties that help shed dead skin cells and reduce comedone formation. The 4% concentration provides moderate efficacy with generally good tolerability for topical acne treatment.
Approved indications
- Acne vulgaris (mild to moderate)
- Acne rosacea (adjunctive)
Common side effects
- Skin irritation and erythema
- Dryness and peeling
- Contact dermatitis
- Bleaching of hair or fabrics
Key clinical trials
- An Observational Clinical Study to Evaluate the Efficacy of the CeraVe Skin Care Line
- The Relationship Between Microbioma Balance and Acne Vulgaris as a New Acne Treatment (PHASE2)
- Evaluation of Topical Encapsulated Benzoyl Peroxide on the Skin Microbiome and Skin Biophysical Properties (PHASE1)
- Comparing Efficacy of Azithromycin and Probiotics for Treatment of Acne Vulgaris (PHASE3)
- Skin Acceptance and Efficacy Assessment of a Topical Product in Acne Treatment When Compared to a Placebo. (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Benzoyl Peroxide 4 % Topical Cream CI brief — competitive landscape report
- Benzoyl Peroxide 4 % Topical Cream updates RSS · CI watch RSS
- Pak Emirates Military Hospital portfolio CI