Therapeutic vaccine
This page covers all Therapeutic vaccine drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting HIV Tat protein, Huntingtin protein (HTT), Mycobacterium tuberculosis antigens.
Targets
HIV Tat protein · Huntingtin protein (HTT) · Mycobacterium tuberculosis antigens · Hepatitis B surface antigen (HBsAg) · Oxidized low-density lipoprotein (oxLDL) and atherosclerotic plaque antigens · Hepatitis B virus antigens · HPV antigens (E6/E7) · Human papillomavirus (HPV) antigens · HBV antigens; TLR4 (via MPL adjuvant) · HIV-1 envelope proteins (gp120, gp41)
Marketed (3)
- TEP · Immungenetics AG · Oncology
TEP is a therapeutic vaccine that works by stimulating the immune system to produce antibodies against the Epstein-Barr virus. - Tat · Barbara Ensoli, MD · Immunology / Infectious Disease
Tat is a therapeutic vaccine based on the HIV Tat protein designed to boost immune responses against HIV-infected cells. - HD Vaccine · Insight Therapeutics, LLC · Neurology
HD Vaccine is a therapeutic vaccine designed to stimulate the immune system to target and eliminate cells expressing huntingtin protein, potentially slowing neurodegeneration in Huntington's disease.
Phase 3 pipeline (21)
- GamTBvac · Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation · Infectious Disease / Immunology
GamTBvac is a therapeutic tuberculosis vaccine that stimulates immune responses against Mycobacterium tuberculosis antigens to enhance host immunity and control infection. - GenHevac-B · ANRS, Emerging Infectious Diseases · Immunology / Infectious Disease
GenHevac-B is a therapeutic hepatitis B vaccine designed to boost immune response in chronically infected patients by presenting hepatitis B surface antigen (HBsAg) to stimulate T-cell and B-cell immunity. - atherosclerosis vaccine · Immunitor LLC · Cardiovascular
An immunotherapeutic vaccine that stimulates the immune system to recognize and attack oxidized lipoproteins and atherosclerotic plaques. - HB-AS02V · Henogen · Immunology / Infectious Disease
HB-AS02V is a therapeutic vaccine designed to stimulate immune responses against hepatitis B surface antigen. - Hepavax-Gene · Chiang Mai University · Virology / Infectious Disease
Hepavax-Gene is a therapeutic hepatitis B vaccine designed to generate immune responses against hepatitis B virus through genetic engineering approaches. - THVD-201 · SK Chemicals Co., Ltd. · Oncology
THVD-201 is a therapeutic vaccine designed to stimulate immune responses against human papillomavirus (HPV) for the treatment of HPV-related cancers. - PR5I · MCM Vaccines B.V. · Immunology / Infectious Disease
PR5I is a therapeutic vaccine designed to stimulate immune responses against pneumococcal serotypes to prevent pneumococcal disease. - Placebo to V920 · Merck Sharp & Dohme LLC · Oncology / Immunology
V920 is a therapeutic vaccine designed to stimulate immune responses against human papillomavirus (HPV) infection. - GSK investigational vaccine GSK1557482A · GlaxoSmithKline · Oncology or Immunology
GSK1557482A is an investigational therapeutic vaccine designed to stimulate immune responses against specific tumor-associated antigens or pathogens. - V7 · Immunitor LLC · Immunology / Infectious Disease
V7 is an immunotherapeutic vaccine designed to stimulate the immune system against HIV infection. - NBP607-TIV · SK Chemicals Co., Ltd. · Immunology / Infectious Disease
NBP607-TIV is a therapeutic influenza vaccine designed to enhance immune response against multiple influenza virus strains. - Placebo to V503 · Merck Sharp & Dohme LLC · Oncology
V503 is a therapeutic vaccine candidate designed to stimulate immune responses against human papillomavirus (HPV) types associated with cervical and other cancers. - HBV-MPL 208129 · GlaxoSmithKline · Immunology / Virology
HBV-MPL 208129 is a therapeutic vaccine that combines hepatitis B virus (HBV) antigens with MPL (monophosphoryl lipid A) adjuvant to stimulate immune responses against chronic HBV infection. - ALVAC-HIV vCP1521 + AIDSVAX · U.S. Army Medical Research and Development Command · Immunology / Infectious Disease
A combination HIV vaccine that uses a recombinant canarypox vector (ALVAC-HIV vCP1521) as a prime followed by a recombinant gp120 protein boost (AIDSVAX) to elicit cellular and humoral immune responses against HIV. - Hillchol vaccine · Bharat Biotech International Limited · Cardiovascular
Hillchol is a therapeutic vaccine designed to induce immune responses against cholesterol and lipid-related antigens to reduce cardiovascular risk. - HB-AS02V vaccine · Henogen · Immunology / Virology
HB-AS02V is a therapeutic vaccine designed to stimulate immune responses against hepatitis B surface antigen to treat chronic hepatitis B infection. - GC3110A(Trivalent) · Green Cross Corporation
GC3110A is a trivalent vaccine designed to stimulate immune responses against multiple targets for therapeutic benefit. - Cervavac as three dose regimen · Serum Institute of India Pvt. Ltd. · Oncology
Cervavac is a therapeutic HPV vaccine that stimulates the immune system to target and eliminate cervical cancer cells expressing human papillomavirus antigens. - NASVAC · Clinical Research Organization, Dhaka, Bangladesh · Virology / Hepatology
NASVAC is a therapeutic vaccine designed to stimulate immune responses against hepatitis B surface antigen (HBsAg) in chronic hepatitis B patients. - IC51 · Valneva Austria GmbH · Oncology / Immunology
IC51 is a therapeutic vaccine that stimulates the immune system to recognize and attack cells infected with human papillomavirus (HPV). - ASP0113 · Astellas Pharma Global Development, Inc. · Immunology / Infectious Disease
ASP0113 is a therapeutic vaccine that stimulates the immune system to recognize and eliminate cells infected with cytomegalovirus (CMV).
Phase 2 pipeline (4)
- AB PREP · Long Neck Medical Enterprises · Infectious Disease
AB PREP is a therapeutic vaccine designed to stimulate an immune response against the SARS-CoV-2 virus. - CYT004-MelQbG10 intra nodal injection · Cytos Biotechnology AG · Oncology
CYT004-MelQbG10 is a therapeutic vaccine designed to stimulate an immune response against melanoma. - CYT003-QbG10 · Cytos Biotechnology AG · Autoimmune diseases
CYT003-QbG10 is a therapeutic vaccine designed to treat autoimmune diseases by modulating the immune response. - Daily oral dose of hepcortespenlisimut-L · Immunitor LLC · Infectious Disease / Virology
Hepcortespenlisimut-L is an oral therapeutic vaccine that stimulates immune responses against hepatitis C virus (HCV) antigens to enhance viral clearance.