What are Synthetic opioid agonist drugs?

Synthetic opioid agonist drugs are pharmacologic agents that share a common mechanism (typically targeting Mu-opioid receptor (OPRM1)). 7 are currently marketed, with 1 more in clinical development.

What are the marketed Synthetic opioid agonist drugs?

Marketed Synthetic opioid agonist drugs include Unrestricted Fentanyl, Methadone Maintenance Therapy, Duragesic reference fentanyl TDS, Methadone Pill, Normal dose of alfentanil hydrochloride, Fentanyl ev.

Synthetic opioid agonist

7 marketed 1 in Phase 3

This page covers all Synthetic opioid agonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Mu-opioid receptor (OPRM1), Mu opioid receptor (μ-opioid receptor), Mu-opioid receptor (μ-OR).

Targets

Mu-opioid receptor (OPRM1) · Mu opioid receptor (μ-opioid receptor) · Mu-opioid receptor (μ-OR) · Mu opioid receptor (μ-OR) · Mu opioid receptor (OPRM1)

Marketed (7)

Unrestricted Fentanyl · Virginia Commonwealth University · Pain management
Fentanyl is a synthetic opioid agonist that binds to mu-opioid receptors in the central nervous system to produce analgesia and sedation.
Methadone Maintenance Therapy · Oregon Health and Science University · Addiction Medicine / Substance Use Disorder
Methadone is a synthetic opioid agonist that binds to mu opioid receptors in the central nervous system to prevent withdrawal symptoms and reduce cravings in opioid-dependent patients.
Duragesic reference fentanyl TDS · University of Maryland, Baltimore · Pain Management
Fentanyl is a synthetic opioid agonist that binds to mu-opioid receptors in the central nervous system to produce analgesia and sedation.
Methadone Pill · Boston Medical Center · Pain Management; Substance Use Disorder
Methadone is a synthetic opioid agonist that binds to mu opioid receptors in the central nervous system to produce analgesia and reduce withdrawal symptoms.
Normal dose of alfentanil hydrochloride · University Hospital, Ghent · Anesthesia and Pain Management
Alfentanil hydrochloride is a potent synthetic opioid agonist that binds to mu (μ) opioid receptors in the central nervous system to produce analgesia and sedation.
Fentanyl ev · Azienda Sanitaria dell'Alto Adige · Pain management, Anesthesia
Fentanyl is a synthetic opioid agonist that binds to mu-opioid receptors in the central nervous system to produce analgesia and sedation.
Mylan generic fentanyl · University of Maryland, Baltimore · Pain Management
Fentanyl is a synthetic opioid that binds to mu opioid receptors in the central nervous system to produce analgesia and sedation.

Phase 3 pipeline (1)

Parenteral /oral methadone ratio 1:2 · L'Hospitalet de Llobregat · Addiction Medicine / Pain Management
Methadone is a synthetic opioid agonist that binds to mu opioid receptors in the central nervous system to produce analgesia and suppress withdrawal symptoms in opioid-dependent patients.