Prostaglandin E1 analog

This page covers all Prostaglandin E1 analog drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Prostaglandin E2 receptor EP2 subtype, Prostaglandin E2 receptor EP3 subtype, Prostaglandin E2 receptor EP4 subtype, Prostanoid receptors (EP receptors), Prostaglandin E receptor (EP receptors).

Targets

Prostaglandin E2 receptor EP2 subtype, Prostaglandin E2 receptor EP3 subtype, Prostaglandin E2 receptor EP4 subtype · Prostanoid receptors (EP receptors) · Prostaglandin E receptor (EP receptors) · Prostaglandin E receptor (EP receptor) · Prostaglandin E receptors (EP1, EP2, EP3, EP4)

Marketed (5)

• Cytotec · Generic (originally Searle/Pfizer) · Immunology
  Synthetic prostaglandin E1 analog that protects gastric mucosa by inhibiting acid secretion and stimulating mucus/bicarbonate, also causes uterine contraction.
• Alprostadil ﹠control · Shanghai 10th People's Hospital · Cardiovascular
  Alprostadil is a prostaglandin E1 analog that vasodilates blood vessels and inhibits platelet aggregation.
• Lipo-PGE1 · West China Hospital · Cardiovascular
  Lipo-PGE1 is a lipid-formulated prostaglandin E1 that promotes vasodilation and improves blood flow by activating prostanoid receptors on vascular smooth muscle and endothelial cells.
• Cytotec (reference drug) · Dong-A ST Co., Ltd. · Gastroenterology
  Cytotec (misoprostol) is a prostaglandin E1 analog that reduces gastric acid secretion and protects the gastric mucosa.
• Prostin (PGE2) tablets · Wolfson Medical Center · Cardiovascular
  Prostin (PGE2) is a prostaglandin E1 analog that binds to prostaglandin receptors to promote vasodilation, inhibit platelet aggregation, and improve blood flow.

Phase 2 pipeline (1)

• Alprostadil 20 micrograms · Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia · Cardiovascular
  Alprostadil is a prostaglandin E1 analog that vasodilates blood vessels and inhibits platelet aggregation.