What are Platinum-based alkylating agent drugs?

Platinum-based alkylating agent drugs are pharmacologic agents that share a common mechanism (typically targeting DNA). 2 are currently marketed, with 12 more in clinical development.

What are the marketed Platinum-based alkylating agent drugs?

Marketed Platinum-based alkylating agent drugs include cis-platinum, Platinum-Based Chemotherapy.

Platinum-based alkylating agent

2 marketed 12 in Phase 3

This page covers all Platinum-based alkylating agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting DNA.

Targets

DNA

Marketed (2)

cis-platinum · Peking University Third Hospital · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA adducts and cross-links, preventing DNA replication and transcription to induce cancer cell death.
Platinum-Based Chemotherapy · Genprex, Inc. · Oncology
Platinum-based chemotherapy drugs form covalent crosslinks with DNA, preventing replication and transcription, thereby inducing cancer cell death.

Phase 3 pipeline (12)

Carboplatin/Paraplatin · Bristol-Myers Squibb · Oncology
Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing cancer cell replication and inducing cell death.
Cisplatin (DDP) · Sun Yat-sen University · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription, thereby inducing cancer cell death.
Inj.Cisplatin · Tata Memorial Hospital · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription in cancer cells.
Cisplatin (CDDP) · Sun Yat-sen University · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription, thereby inducing cancer cell death.
Cisplatin 2 · Sun Yat-sen University · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription in cancer cells.
cisplatin i.p. · West China Second University Hospital · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription in cancer cells.
Cisplatin/Platinol · Bristol-Myers Squibb · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and triggering cancer cell death.
Cisplatin（adjuvant） · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and triggering cancer cell death.
Cisplatin-based induction chemotherapy · Ming-Yuan Chen · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription in cancer cells.
Chemotherapy (Cisplatin) · Insel Gruppe AG, University Hospital Bern · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription, thereby inducing cancer cell death.
Cisplatin Chemotherapy · Cedars-Sinai Medical Center · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing cancer cell replication and inducing cell death.
Drug：Cisplatin · Sun Yat-sen University · Oncology
Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription, thereby inducing cancer cell death.