partial opioid agonist

This page covers all partial opioid agonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting mu-opioid receptor, kappa-opioid receptor, Mu-opioid receptor (μ-OR), mu-opioid receptor.

Targets

mu-opioid receptor, kappa-opioid receptor · Mu-opioid receptor (μ-OR) · mu-opioid receptor

Marketed (3)

• Subutex · Indivior · Pain · 800
  Buprenorphine is a partial agonist at mu-opioid receptors and antagonist at kappa-opioid receptors.
• Subutex · Purdue Pharma Lp · Neuroscience · 800
  Buprenorphine binds to mu-opioid receptors as a partial agonist and kappa-opioid receptors as an antagonist.
• Buprenorphine (Subutex) · Indivior Inc. · Psychiatry / Addiction Medicine
  Buprenorphine is a partial opioid agonist that binds to mu-opioid receptors in the brain, reducing cravings and withdrawal symptoms while producing a lower risk of overdose compared to full opioid agonists.

Phase 3 pipeline (1)

• PBO-N/PBO-B · Alkermes, Inc. · Pain
  PBO-N/PBO-B is a partial opioid agonist.