Oxazolidinone antibiotic

This page covers all Oxazolidinone antibiotic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Bacterial 50S ribosomal subunit, Bacterial 50S ribosomal subunit (23S rRNA), Bacterial 70S ribosome (peptidyl transferase center).

Targets

Bacterial 50S ribosomal subunit · Bacterial 50S ribosomal subunit (23S rRNA) · Bacterial 70S ribosome (peptidyl transferase center) · 50S ribosomal subunit · Bacterial 70S ribosome

Marketed (9)

• Tedizolid IV · University of Southern California · Infectious Disease
  Tedizolid inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.
• Linezolid (L) · Shenzhen Third People's Hospital · Infectious Disease
  Linezolid inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.
• Linezolid (LZD) · Wuhan Pulmonary Hospital · Infectious Disease
  Linezolid inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.
• Linezolid Injectable Product · Fundacion Clinic per a la Recerca Biomédica · Infectious Disease
  Linezolid inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.
• Oral Suspension Tedizolid Phosphate · Merck Sharp & Dohme LLC · Infectious Disease
  Tedizolid phosphate is a prodrug that is converted to tedizolid, an oxazolidinone antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit.
• Sivextro 200 milligrams Oral Tablet · Fundacion Clinic per a la Recerca Biomédica · Infectious Disease
  Sivextro (tedizolid) inhibits bacterial protein synthesis by binding to the bacterial ribosome.
• Tedizolid PO · University of Southern California · Infectious Disease
  Tedizolid inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.
• Linezolid antimicrobial-lock solution · Clinica Universidad de Navarra, Universidad de Navarra · Infectious Disease
  Linezolid inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation and bacterial growth.
• linezolid (Zyvox) · Pfizer · Infectious Disease
  Linezolid inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.

Phase 3 pipeline (5)

• Intravenous linezolid · Arpida AG · Infectious Disease
  Linezolid inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.
• Tedizolid Phophate · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) · Infectious Diseases
  Tedizolid phosphate is an oxazolidinone antibiotic that inhibits protein synthesis in bacteria by binding to the 50S ribosomal subunit.
• TR-701 FA · Trius Therapeutics LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) · Infectious Disease
  TR-701 FA is a prodrug of TR-700 that inhibits bacterial protein synthesis by binding to the bacterial ribosome.
• Tedizolid (BAY119-2631) · Bayer · Infectious Disease
  Tedizolid is an oxazolidinone antibiotic that inhibits protein synthesis in bacteria.
• intravenous iclaprim or intravenous linezolid · Arpida AG · Infectious disease
  Iclaprim inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit.