Opioid receptor antagonist

This page covers all Opioid receptor antagonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Opioid receptors (mu, delta, kappa), Mu opioid receptor (primary); delta and kappa opioid receptors, Mu, delta, and kappa opioid receptors.

Targets

Opioid receptors (mu, delta, kappa) · Mu opioid receptor (primary); delta and kappa opioid receptors · Mu, delta, and kappa opioid receptors · Opioid receptor · kappa opioid receptor · Kappa opioid receptor

Marketed (8)

• long-lasting injectable naltrexone · State University of New York - Upstate Medical University · Psychiatry / Addiction Medicine
  Naltrexone is an opioid receptor antagonist that blocks the effects of opioids and reduces cravings for opioid use.
• Oral Naltrexone · New York State Psychiatric Institute · Psychiatry / Addiction Medicine / Immunology
  Oral naltrexone is an opioid receptor antagonist that blocks the effects of opioids and endogenous opioid peptides in the central nervous system.
• XR-NTX 380 mg, intramuscular injection · University of Pennsylvania · Psychiatry / Addiction Medicine
  XR-NTX 380 mg is an extended-release formulation of naltrexone that blocks opioid receptors to prevent opioid use and reduce cravings in opioid use disorder.
• naltrexone (Revia) · University of North Carolina, Chapel Hill · Psychiatry / Addiction Medicine
  Naltrexone is an opioid receptor antagonist that blocks the effects of opioids and endogenous opioid peptides in the central nervous system.
• Naltrexone Oral Product · Texas Tech University · Psychiatry / Addiction Medicine
  Naltrexone is an opioid receptor antagonist that blocks the effects of opioids and endogenous opioid peptides in the central nervous system.
• Naltrexone Pill · Albert Einstein Healthcare Network · Psychiatry / Addiction Medicine
  Naltrexone is an opioid receptor antagonist that blocks the effects of opioids and reduces cravings for alcohol and opioids.
• Nalmefene HCl injection · Leiden University Medical Center · Addiction Medicine / Emergency Medicine
  Nalmefene is a competitive opioid receptor antagonist that blocks the effects of opioids by binding to opioid receptors with high affinity and specificity.
• Naltrexone Tablet and Placebo Patch · The Scripps Research Institute · Addiction Medicine / Psychiatry
  Naltrexone blocks opioid receptors to reduce cravings and reward-seeking behavior, while the placebo patch serves as a control in this combination formulation.

Phase 3 pipeline (2)

• Naltrexone intramuscular suspension · University of Oslo · Psychiatry
  Naltrexone is an opioid receptor antagonist that blocks the action of opioids at their receptor sites.
• Naloxone Nasal Spray · Pocket Naloxone Corp · Emergency Medicine / Toxicology
  Naloxone is a competitive opioid receptor antagonist that rapidly blocks opioid effects and reverses opioid overdose.

Phase 2 pipeline (3)

• A. CNS 7056 · Paion UK Ltd. · Pain
  CNS 7056 is a kappa opioid receptor antagonist.
• Effentora® · Cephalon · Neurology
  A selective kappa opioid receptor antagonist.
• CNS 7056 · Paion UK Ltd. · Pain
  CNS 7056 is a kappa opioid receptor antagonist.