Opioid analgesic combined with local anesthetic

This page covers all Opioid analgesic combined with local anesthetic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Mu opioid receptor (fentanyl); voltage-gated sodium channels (bupivacaine), Mu-opioid receptor (tramadol); voltage-gated sodium channels (ropivacaine).

Targets

Mu opioid receptor (fentanyl); voltage-gated sodium channels (bupivacaine) · Mu-opioid receptor (tramadol); voltage-gated sodium channels (ropivacaine)

Marketed (2)

• Fentanyl and bupivacaine · Hospital Central Dr. Luis Ortega · Anesthesia and Pain Management
  Fentanyl is a potent opioid agonist that binds mu opioid receptors to provide analgesia, while bupivacaine is a local anesthetic that blocks sodium channels to prevent nerve signal transmission.
• Tramadol with ropivacaine · Aristotle University Of Thessaloniki · Pain management
  Tramadol provides systemic opioid analgesia while ropivacaine delivers local anesthetic blockade of nerve conduction at the site of administration.