What are Nucleotide reverse transcriptase inhibitor drugs?

Nucleotide reverse transcriptase inhibitor drugs are pharmacologic agents that share a common mechanism (typically targeting Hepatitis B virus reverse transcriptase). 4 are currently marketed, with 4 more in clinical development.

What are the marketed Nucleotide reverse transcriptase inhibitor drugs?

Marketed Nucleotide reverse transcriptase inhibitor drugs include Besifovir dipivoxil, Adefovir Dipivoxil Tablets, Adefor dipivoxil, Adefovir dipivoxil (adefovir).

Nucleotide reverse transcriptase inhibitor

4 marketed 3 in Phase 3 1 in Phase 2

This page covers all Nucleotide reverse transcriptase inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Hepatitis B virus reverse transcriptase, Hepatitis B virus reverse transcriptase and DNA polymerase, Hepatitis B virus reverse transcriptase / DNA polymerase.

Targets

Hepatitis B virus reverse transcriptase · Hepatitis B virus reverse transcriptase and DNA polymerase · Hepatitis B virus reverse transcriptase / DNA polymerase · HIV reverse transcriptase · Reverse transcriptase · Hepatitis B virus DNA polymerase / reverse transcriptase · HBV DNA polymerase

Marketed (4)

Besifovir dipivoxil · IlDong Pharmaceutical Co Ltd · Virology / Hepatology
Besifovir dipivoxil is a nucleotide reverse transcriptase inhibitor that blocks hepatitis B virus replication by inhibiting the viral reverse transcriptase enzyme.
Adefovir Dipivoxil Tablets · Sun Yat-sen University · Virology / Hepatology
Adefovir dipivoxil is a nucleotide reverse transcriptase inhibitor that blocks viral DNA polymerase, preventing replication of hepatitis B virus.
Adefor dipivoxil · GlaxoSmithKline · Virology / Hepatology
Adeforvir dipivoxil is a nucleotide reverse transcriptase inhibitor that blocks viral replication in hepatitis B by inhibiting the reverse transcriptase enzyme.
Adefovir dipivoxil (adefovir) · Merck Sharp & Dohme LLC · Virology / Infectious Disease
Adefovir dipivoxil is a nucleotide reverse transcriptase inhibitor that blocks viral DNA polymerase activity in hepatitis B virus.

Phase 3 pipeline (3)

Suraxavir Marboxil · Jiangxi Kvvit Pharmaceutical Co., Ltd. · Infectious diseases
Suraxavir Marboxil is a prodrug of suraxavir, a nucleotide reverse transcriptase inhibitor.
Tenofovir gel · National Institute of Allergy and Infectious Diseases (NIAID) · Infectious disease
Tenofovir gel works by inhibiting the replication of HIV by blocking the action of reverse transcriptase.
Adefovir (ADV) · Bristol-Myers Squibb · Virology / Infectious Disease
Adefovir is a nucleotide reverse transcriptase inhibitor that blocks viral DNA polymerase, preventing replication of hepatitis B virus.

Phase 2 pipeline (1)

Adefovir tablets · GlaxoSmithKline · Infectious Disease
Adefovir works by inhibiting the replication of the hepatitis B virus.