Reverse transcriptase — Drug Target

All drugs that target Reverse transcriptase — marketed and clinical-stage. Includes 7 drug classes acting on this target.

Drug classes

Non-nucleoside reverse transcriptase inhibitor (NNRTI) · NRTI · non-nucleoside reverse transcriptase inhibitor · Nucleotide reverse transcriptase inhibitor · NRTI (nucleoside reverse transcriptase inhibitor) · Nucleoside reverse transcriptase inhibitors (NRTIs) · Non-nucleoside reverse transcriptase inhibitor

Phase 3 pipeline (8)

• TMC125 · Tibotec Pharmaceuticals, Ireland · Non-nucleoside reverse transcriptase inhibitor (NNRTI) · Infectious Disease
  TMC125 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that blocks HIV replication.
• Rilpivirine Tablets · ViiV Healthcare · Non-nucleoside reverse transcriptase inhibitor (NNRTI) · Infectious Disease
  Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that works by blocking the replication of the HIV virus.
• TRUVADA™ or EPZICOM™/KIVEXA™ · Merck Sharp & Dohme LLC · NRTI · Infectious Disease
  TRUVADA and EPZICOM/KIVEXA are antiretroviral medications used to treat HIV-1 infection by inhibiting viral replication.
• Nevirapine and mulitvitamins · National Institute of Allergy and Infectious Diseases (NIAID) · non-nucleoside reverse transcriptase inhibitor · Infectious Disease
  Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that works by blocking the replication of the HIV virus.
• Rilpivirine (RPV) · Janssen Infectious Diseases BVBA · Non-nucleoside reverse transcriptase inhibitor (NNRTI) · Infectious Diseases
  Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that blocks the replication of HIV-1 by binding to the reverse transcriptase enzyme.
• Tenofovir gel · National Institute of Allergy and Infectious Diseases (NIAID) · Nucleotide reverse transcriptase inhibitor · Infectious disease
  Tenofovir gel works by inhibiting the replication of HIV by blocking the action of reverse transcriptase.
• Treatment and prophylaxis · Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia · NRTI (nucleoside reverse transcriptase inhibitor) · Infectious Disease
  This drug works by inhibiting the replication of the human immunodeficiency virus (HIV).
• Switch from tenofovir to abacavir · Germans Trias i Pujol Hospital · NRTI · Infectious Diseases
  Abacavir is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the replication of HIV.

Phase 2 pipeline (3)

• Baseline ART · Frontier Biotechnologies Inc. · Nucleoside reverse transcriptase inhibitors (NRTIs) · Infectious Diseases
  Baseline ART works by suppressing the replication of the human immunodeficiency virus (HIV) through the inhibition of reverse transcriptase.
• Etravirine Tablets · IRCCS Eugenio Medea · Non-nucleoside reverse transcriptase inhibitor · Infectious Disease
  Non-nucleoside reverse transcriptase inhibitor
• HAART containing nevirapine · The HIV Netherlands Australia Thailand Research Collaboration · Non-nucleoside reverse transcriptase inhibitor · Infectious Disease
  Non-nucleoside reverse transcriptase inhibitor