Anticholinergic agent / Muscarinic receptor antagonist

This page covers all Anticholinergic agent / Muscarinic receptor antagonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Muscarinic acetylcholine receptors (M1, M3, M5), M2 and M3 muscarinic receptors, M2 and M3 muscarinic acetylcholine receptors.

Targets

Muscarinic acetylcholine receptors (M1, M3, M5) · M2 and M3 muscarinic receptors · M2 and M3 muscarinic acetylcholine receptors · Muscarinic acetylcholine receptors (M1-M5, primarily M3 in ocular tissue) · M3 muscarinic receptor · Muscarinic acetylcholine receptors (M1-M5, primarily M1 and M3) · Muscarinic acetylcholine receptors (M1-M5) · Muscarinic acetylcholine receptors (M1, M3)

Marketed (5)

• Atropine Sulfate 0.04% Eye Drop · Shanghai Eye Disease Prevention and Treatment Center · Ophthalmology
  Atropine blocks muscarinic acetylcholine receptors in the eye to dilate the pupil and paralyze accommodation.
• Tolterodine Tartrate ER · University of California, San Francisco · Urology
  Tolterodine tartrate is a muscarinic receptor antagonist that blocks acetylcholine signaling in the bladder to reduce involuntary contractions and urinary urgency.
• Detrol LA · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Urology
  Detrol LA is a muscarinic receptor antagonist that blocks acetylcholine signaling in the bladder to reduce involuntary muscle contractions and urinary urgency.
• Tolterodine 6 · KYU-SUNG LEE · Urology
  Tolterodine is a muscarinic receptor antagonist that blocks acetylcholine signaling in the bladder to reduce involuntary contractions and urinary urgency.
• Atropine 1% · Massachusetts Eye and Ear Infirmary · Ophthalmology
  Atropine blocks muscarinic acetylcholine receptors to inhibit parasympathetic activity, causing pupil dilation and cycloplegia when applied topically to the eye.

Phase 3 pipeline (4)

• Urotol® · R-Pharm · Urology
  Urotol is a muscarinic receptor antagonist used to treat overactive bladder.
• Atropine sulfate eye drops 0.02% · Oupushifang Pharmaceutical Technology Co., Ltd. · Ophthalmology
  Atropine blocks muscarinic acetylcholine receptors in the eye to dilate the pupil and paralyze accommodation, slowing myopia progression in children.
• Atropine Sulfate 02 · LitePharmTech Co., Ltd. · Emergency Medicine, Ophthalmology, Cardiology
  Atropine sulfate is an anticholinergic agent that blocks muscarinic acetylcholine receptors to inhibit parasympathetic nervous system activity.
• Atropine sulfate eye drops 0.01% · Oupushifang Pharmaceutical Technology Co., Ltd. · Ophthalmology
  Atropine is a muscarinic acetylcholine receptor antagonist that blocks parasympathetic signaling in the eye to inhibit accommodation and pupil constriction.

Patent intelligence

• muscarinic receptor antagonist patent landscape — aggregated cliff calendar, attackable patents, originator estates