mRNA vaccine
This page covers all mRNA vaccine drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting SARS-CoV-2 spike protein, SARS-CoV-2 spike protein (S protein), SARS-CoV-2 spike protein (XBB.1.5 variant).
Targets
SARS-CoV-2 spike protein · SARS-CoV-2 spike protein (S protein) · SARS-CoV-2 spike protein (XBB.1.5 variant) · HPV16 and HPV18 antigens (E6 and E7 proteins) · SARS-CoV-2 spike protein (original strain and Omicron BA.1 variant) · SARS-CoV-2 · SARS-CoV-2 spike protein (variant-specific) · SARS-CoV-2 spike protein (original strain and Omicron BA.4-5 variants) · SARS-CoV-2 virus · Spike protein of SARS-CoV-2
Marketed (31)
- COMIRNATY intramuscular injection · Pfizer · 4367.0
- Homologous mRNA booster vaccine · Tan Tock Seng Hospital · Immunology / Infectious Disease
A homologous mRNA booster vaccine that encodes viral antigens to enhance and broaden immune responses in individuals previously vaccinated against COVID-19. - BNT162b2 Pfizer-BioNTech/Comirnaty · KK Women's and Children's Hospital · Immunology / Infectious Disease
BNT162b2 is an mRNA vaccine that instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response to prevent COVID-19 infection. - Spikevax Omicron XBB.1.5 · Jules Bordet Institute · Immunology / Infectious Disease
Spikevax Omicron XBB.1.5 is an mRNA vaccine that instructs cells to produce the spike protein of the XBB.1.5 Omicron variant of SARS-CoV-2, triggering an immune response to protect against COVID-19 infection. - Variant-adapted BNT162b2 (Omicron XBB.1.5) 10 microgram dose · Pfizer · Immunology
- BNT162b5 Bivalent (WT/OMI BA.2) · Pfizer · Immunology
- mRNA-1283 · ModernaTX, Inc. · Oncology
mRNA-1283 is a self-amplifying mRNA vaccine that encodes human papillomavirus (HPV) antigens to stimulate immune responses against HPV-infected cells. - Comirnaty Omicron XBB.1.5 · Jules Bordet Institute · Immunology / Infectious Disease
Comirnaty Omicron XBB.1.5 is an mRNA vaccine that instructs cells to produce the spike protein of the XBB.1.5 Omicron variant, triggering immune recognition and antibody production against this SARS-CoV-2 strain. - Comirnaty Original/Omicron BA.1 · Jules Bordet Institute · Immunology / Infectious Disease
This bivalent mRNA vaccine encodes spike proteins from both the original SARS-CoV-2 strain and the Omicron BA.1 variant to elicit immune responses against multiple viral lineages. - BNT162b2 (Omi XBB.1.5) · Pfizer · Immunology
- Variant-adapted BNT162b2 (Omicron XBB.1.5) 3 microgram dose · Pfizer · Immunology
- The Pfizer mRNA-based BNT162b2 vaccine · dafna yahav · Immunology / Infectious Disease
BNT162b2 is an mRNA vaccine that instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response to prevent COVID-19 infection. - mRNA-1273 vaccine · University Health Network, Toronto · Immunology / Infectious Disease
mRNA-1273 is an mRNA vaccine that instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response to prevent COVID-19 infection. - mRNA-1273 Variant-containing Formulation · ModernaTX, Inc. · Immunology / Infectious Disease
mRNA-1273 Variant-containing Formulation encodes instructions for cells to produce spike proteins from SARS-CoV-2 variants, triggering an immune response against those variants. - Heterologous mRNA booster vaccine · Tan Tock Seng Hospital · Immunology / Infectious Disease
A heterologous mRNA booster vaccine uses messenger RNA from a different pathogen or platform to enhance immune response in individuals previously primed with another vaccine. - Comirnaty Original/Omicron BA.4-5 · Jules Bordet Institute · Immunology / Infectious Disease
This bivalent mRNA vaccine encodes spike proteins from the original SARS-CoV-2 strain and the Omicron BA.4-5 variants to elicit adaptive immune responses against multiple circulating viral lineages. - mRNA-1273 · Assistance Publique - Hôpitaux de Paris · Immunology / Infectious Disease
mRNA-1273 is a lipid nanoparticle-formulated messenger RNA vaccine that encodes the SARS-CoV-2 spike protein, instructing cells to produce the antigen and trigger adaptive immune responses. - BNT162b2 BA.4/5 bivalent · Pfizer · Immunology
- BioNTech - Pfizer COVID-19 vaccine · University of Birmingham · Immunology / Infectious Disease
This mRNA vaccine instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response that protects against COVID-19 infection. - Pfizer-COVID-19 Vaccine · National Heart, Lung, and Blood Institute (NHLBI) · Immunology / Infectious Disease
This mRNA vaccine instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response that protects against COVID-19 infection. - Combination BNT162b2 and BNT162b2 OMI · Pfizer · Infectious Disease
A combination of two mRNA-based vaccines that work together to prevent and treat COVID-19. - BNT162b2 (Omi KP.2) · Pfizer Inc. · Immunology
- COMIRNATY - BioNTech Manufacturing GmbH · Jens D Lundgren, MD · Immunology / Infectious Disease
COMIRNATY is an mRNA vaccine that instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response to prevent COVID-19 infection. - Spikevax bivalent Original/Omicron BA.1 · Jules Bordet Institute · Immunology / Infectious Disease
This bivalent mRNA vaccine encodes spike proteins from both the original SARS-CoV-2 strain and the Omicron BA.1 variant to elicit immune responses against multiple viral variants. - COVID-19 mRNA vaccine · Vaccine Company, Inc. · Immunology / Infectious Disease
The vaccine delivers mRNA encoding the SARS-CoV-2 spike protein, which is translated by host cells to trigger adaptive immune responses against COVID-19. - Moderna mRNA-1273 COVID-19 vaccine · National Institute of Allergy and Infectious Diseases (NIAID) · Immunology / Infectious Disease
mRNA-1273 is an mRNA vaccine that instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response to prevent COVID-19 infection. - BNT162b5 Bivalent (Original/OMI BA.4/BA.5) · Pfizer · Infectious Disease
Targets the SARS-CoV-2 virus to prevent and treat COVID-19 - bivalent BNT162b2 (original/Omi BA.4/BA.5) · Pfizer · Immunology
- BNT162b2 Bivalent (WT/OMI BA.1) · Pfizer · Immunology
- BNT162b2 Bivalent (original/Omicron BA.4/BA.5) 30 mcg · Pfizer · Immunology
Stimulates the body's immune system to produce antibodies against the SARS-CoV-2 virus. - BNT162b7 Bivalent (Original/OMI BA.4/BA.5) · Pfizer · Infectious Disease
BNT162b7 Bivalent is a mRNA-based vaccine targeting SARS-CoV-2 spike protein.
Phase 3 pipeline (16)
- Comirnaty Vaccine · Clover Biopharmaceuticals AUS Pty · Immunology / Infectious Disease
Comirnaty is an mRNA vaccine that instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response to prevent COVID-19 infection. - BNT324 · BioNTech SE · Immunology / Infectious Disease
BNT324 is an mRNA vaccine designed to elicit an immune response against RSV (respiratory syncytial virus) by encoding viral antigens. - mRNA-1283.222 · ModernaTX, Inc. · Infectious Diseases
mRNA-1283.222 is a messenger RNA-based vaccine that encodes for a specific protein to stimulate an immune response. - mRNA-1345 · ModernaTX, Inc. · Infectious Disease
mRNA-1345 is an mRNA-based vaccine designed to prevent COVID-19 infection by inducing an immune response against the SARS-CoV-2 virus. - PTX-COVID19-B · Providence Therapeutics Holdings Inc. · Immunology / Infectious Disease
PTX-COVID19-B is an mRNA vaccine that encodes viral proteins to stimulate immune responses against SARS-CoV-2. - mRNA-1283.815 · ModernaTX, Inc. · Infectious disease
mRNA-1283.815 is a messenger RNA-based vaccine that encodes for a specific protein to stimulate an immune response. - Bivalent Moderna · Murdoch Childrens Research Institute · Immunology / Infectious Disease
Bivalent Moderna is a bivalent mRNA vaccine that encodes antigens targeting two variants of SARS-CoV-2 to elicit adaptive immune responses. - Investigational mRNA-1273.815 · ModernaTX, Inc. · Immunology / Infectious Disease
mRNA-1273.815 is an mRNA vaccine encoding modified spike proteins designed to elicit immune responses against SARS-CoV-2 variants. - LVRNA009 · AIM Vaccine Co., Ltd. · Immunology/Oncology
LVRNA009 is an mRNA vaccine designed to stimulate immune responses against specific disease targets through encoded antigen expression. - BNT162b2.B.1.351 · BioNTech SE · Immunology / Infectious Disease
BNT162b2.B.1.351 is an mRNA vaccine encoding a modified spike protein from the B.1.351 (Beta) variant of SARS-CoV-2, designed to elicit immune responses against this variant. - Alpharix® Tetra · ModernaTX, Inc. · Immunology / Infectious Disease or Oncology
Alpharix Tetra is a multivalent mRNA vaccine designed to stimulate immune responses against multiple disease targets simultaneously. - mRNA vaccine BNT162b2 (Pfizer) · CanSino Biologics Inc. · Immunology / Infectious Disease
BNT162b2 is an mRNA vaccine that instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response to prevent COVID-19 infection. - mRNA-1403 · ModernaTX, Inc. · Infectious Disease
mRNA-1403 is an mRNA-based vaccine designed to encode for the SARS-CoV-2 spike protein. - BNT162b2 (Pfizer) · Federal University of Espirito Santo · Immunology / Infectious Disease
BNT162b2 is an mRNA vaccine that instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response to prevent COVID-19 infection. - Influsplit® Tetra · ModernaTX, Inc. · Immunology / Infectious Disease
Influsplit® Tetra is a quadrivalent mRNA vaccine that encodes influenza virus surface antigens to stimulate immune responses against four strains of influenza. - Licensed Spikevax Vaccine · ModernaTX, Inc. · Immunology / Infectious Disease
Spikevax is an mRNA vaccine that instructs cells to produce the SARS-CoV-2 spike protein, triggering an immune response to protect against COVID-19 infection.
Phase 2 pipeline (7)
- Biological: mRNA-1273 · ModernaTX, Inc. · Infectious Disease
mRNA-based vaccine that encodes for the SARS-CoV-2 spike protein - Pfizer COVID-19 mRNA vaccine · Methodist Health System · Infectious Disease
mRNA vaccine that encodes for the SARS-CoV-2 spike protein - ARCT-021 Dose 1 · Arcturus Therapeutics, Inc. · Infectious Diseases
ARCT-021 is a mRNA-based vaccine. - BNT327 Optimized Dose · BioNTech SE · Infectious Disease
BNT327 is a mRNA-based vaccine that encodes for the SARS-CoV-2 spike protein. - BNT162b1 · BioNTech SE · Infectious Disease
mRNA-based vaccine - A zoster mRNA vaccine SYS6017 · CSPC Megalith Biopharmaceutical Co.,Ltd. · Immunology / Infectious Disease
SYS6017 is an mRNA vaccine that encodes varicella-zoster virus (VZV) antigens to stimulate adaptive immune responses against herpes zoster. - BNT166a · BioNTech SE · Oncology
BNT166a is an mRNA vaccine designed to encode tumor-associated antigens and stimulate anti-tumor immune responses.