Mood stabilizer

This page covers all Mood stabilizer drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Inositol-1(or 4)-monophosphatase 1, Glycogen synthase kinase-3, Inositol monophosphatase, GSK-3 (glycogen synthase kinase-3), Glycogen synthase kinase-3 (GSK-3), inositol monophosphatase.

Targets

Inositol-1(or 4)-monophosphatase 1, Glycogen synthase kinase-3 · Inositol monophosphatase, GSK-3 (glycogen synthase kinase-3) · Glycogen synthase kinase-3 (GSK-3), inositol monophosphatase · GSK-3 (glycogen synthase kinase-3), inositol monophosphatase

Marketed (4)

• Lithobid · Generic (multiple manufacturers) · Immunology
• Lithium (LI) · Weill Medical College of Cornell University · Psychiatry
  Lithium modulates intracellular signaling pathways, particularly inhibiting inositol monophosphatase and glycogen synthase kinase-3 (GSK-3), which alters neurotransmitter activity and neuroprotective processes in the brain.
• Lithium Carbonate Pill · Shanghai Mental Health Center · Psychiatry
  Lithium carbonate modulates intracellular signaling pathways, particularly inhibiting inositol monophosphatase and glycogen synthase kinase-3 (GSK-3), which stabilizes mood and reduces manic and depressive episodes.
• Placebo plus Lithium · Shanghai Mental Health Center · Psychiatry
  Lithium modulates intracellular signaling pathways, particularly inhibiting glycogen synthase kinase-3 (GSK-3) and affecting monoamine neurotransmitter systems to stabilize mood.

Phase 3 pipeline (7)

• lithium or lamotrigine · University of Aarhus · Psychiatry
  Lithium is a mood stabilizer that works by affecting the levels of certain neurotransmitters in the brain, such as serotonin and dopamine.
• Lithium Carbonate Capsule · University of Milan · Psychiatry
  Lithium carbonate modulates intracellular signaling pathways, particularly inhibiting inositol monophosphatase and glycogen synthase kinase-3 (GSK-3), which alters neurotransmitter activity and neuroprotective gene expression.
• adequate mood stabilizer · AstraZeneca · Psychiatry
  This drug stabilizes mood by modulating neurotransmitter activity.
• divalproex (mood stabilizer) · AstraZeneca · Neurology
  Divalproex works by stabilizing mood by modulating the activity of neurotransmitters in the brain.
• placebo+valproate · National Cheng-Kung University Hospital · Neurology
  Valproate is a mood stabilizer that works by reducing the activity of certain brain chemicals.
• SODIUM DIVALPROATE · Sanofi · Neurology
  Sodium valproate is a mood stabilizer that works by reducing the activity of certain brain chemicals that cause mania and seizures.
• SPN-810 (36 mg) · Supernus Pharmaceuticals, Inc. · Psychiatry
  SPN-810 is a proprietary formulation of a divalproex sodium extended-release product designed to treat disruptive mood dysregulation disorder (DMDD).