Human Immunoglobulin G [EPC]
This page covers all Human Immunoglobulin G [EPC] drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Fc receptors and complement system (indirect mechanism via antibody delivery), Fc receptors, complement system, pathogenic antigens and antibodies, Human thymocytes and T lymphocyte surface antigens (CD2, CD3, CD4, CD8, HLA-DR).
Targets
Fc receptors and complement system (indirect mechanism via antibody delivery) · Fc receptors, complement system, pathogenic antigens and antibodies · Human thymocytes and T lymphocyte surface antigens (CD2, CD3, CD4, CD8, HLA-DR) · Hyaluronic acid in subcutaneous tissue; immunoglobulin G replacement · Multiple pathogenic antigens (polyvalent) · Rabies virus glycoprotein · Fc receptors, pathogenic antigens and antibodies · Fc receptors and complement system (via IgG antibodies) · Digoxin (cardiac glycoside) · Respiratory syncytial virus (RSV) surface proteins
Marketed (24)
- Human immunoglobulin · Centre Hospitalier St Anne
- Anti Thymocyte Globulin · Novartis Pharmaceuticals
- Gammaplex (5%) · Bio Products Laboratory · Immunology
Gammaplex is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by delivering pooled human antibodies to boost immune function. - HUMAN IMMUNOGLOBULIN G
- PRIVIGEN (CSL Behring) · Hospices Civils de Lyon · Immunology
PRIVIGEN is an intravenous immunoglobulin (IVIg) that provides passive immunity by supplying pooled human antibodies to modulate immune responses and replace deficient immunoglobulins. - Anti-Human Thymocyte Immunoglobulin, Rabbit · Peking Union Medical College Hospital · Immunology
This rabbit-derived polyclonal antibody depletes T lymphocytes by binding to antigens on human thymocytes and T cells, thereby suppressing the immune response. - HyQvia · Takeda · Immunology
- IgPro · CSL Behring · Immunology
IgPro is an intravenous immunoglobulin (IVIG) product that provides passive immunity by supplying pooled human antibodies to help fight infections and modulate immune responses. - MIS · Blood Transfusion Centre of Slovenia · Hematology / Immunology
MIS is a blood product derived from donated human blood that restores or replaces deficient blood components. - Botulinum neurotoxin · University of Miami
- Rabies immune globulin (human) · Sanofi Pasteur, a Sanofi Company · Immunology; Infectious Disease
Rabies immune globulin provides passive immunization by supplying human antibodies that neutralize rabies virus and prevent its progression to the central nervous system. - Flebogamma 5% DIF · Instituto Grifols, S.A. · Immunology
Flebogamma 5% DIF is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by supplying pooled human antibodies to modulate immune responses and replace deficient immunoglobulins. - Cuvitru 20 % Injectable Solution · University of Edinburgh · Immunology
Cuvitru is a human immunoglobulin (antibody) replacement therapy that provides passive immunity by supplying functional antibodies to patients with primary immunodeficiency. - Digoxin immune fab · National Institute on Aging (NIA) · Cardiovascular; Toxicology
Digoxin immune fab binds to and neutralizes circulating digoxin, preventing its toxic effects by forming inactive complexes that are renally eliminated. - RSV Polyclonal Immunoglobulin · National Institute of Allergy and Infectious Diseases (NIAID) · Immunology / Infectious Disease
RSV polyclonal immunoglobulin provides passive immunity by supplying antibodies that bind to respiratory syncytial virus and neutralize its infectivity. - human histaglobulin · Hangzhou Grand Biologic Pharmaceutical, Inc. · Immunology; Allergy
Human histaglobulin is a polyclonal immunoglobulin preparation that modulates immune responses by providing passive immunization and stabilizing mast cells to reduce histamine release. - IgM rich Immunoglobin · Sir Takhtasinhji General Hospital · Immunology
IgM-rich immunoglobulin provides passive immune support by supplying IgM antibodies to enhance complement activation and opsonization of pathogens. - Intravenous immune globulin G · Rutgers, The State University of New Jersey · Immunology / Hematology
Intravenous immune globulin G (IVIG) provides passive immunity by delivering pooled immunoglobulin G antibodies from multiple donors to boost immune function and modulate inflammatory responses. - Anthrax Immune Globulin · National Institutes of Health Clinical Center (CC) · Infectious Disease; Immunology
Anthrax Immune Globulin provides passive immunization by supplying antibodies that neutralize anthrax toxins and enhance clearance of Bacillus anthracis. - HyperRAB · Bio Products Laboratory · Infectious Disease / Immunology
HyperRAB is a rabies immunoglobulin (human) that provides passive immunity by supplying antibodies against rabies virus. - Immune Globulin (Human) · Grifols Therapeutics LLC · Immunology
Immune Globulin (Human) provides passive immunization by supplying pooled human antibodies to enhance immune function and neutralize pathogens. - Asceniv™ · ADMA Biologics, Inc. · Immunology
Asceniv is an intravenous immunoglobulin (IVIG) replacement therapy that provides polyclonal antibodies to boost immune function in patients with primary immunodeficiency. - IgPro20 · CSL Behring · Immunology
IgPro20 is a subcutaneous immunoglobulin replacement therapy that provides passive immunity by delivering polyclonal human immunoglobulins to patients with primary immunodeficiency. - abatacept (ABA) · Bristol-Myers Squibb · Immunology
Abatacept is a fusion protein that blocks T-cell costimulation by binding to CD80/CD86 on antigen-presenting cells, thereby inhibiting T-cell activation and proliferation.
Phase 3 pipeline (39)
- IV treatment with IGSC, 10% · Baxalta now part of Shire · Immunology
IGSC 10% is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by supplying pooled human antibodies to help regulate immune function and fight infections. - IGIV GAMUNEX®-C · Baxalta now part of Shire · Immunology
IGIV Gamunex-C is an intravenous immunoglobulin (IVIG) that provides passive immunity by supplying pooled human antibodies to help patients fight infections and modulate immune responses. - IVIG-PEG · Grifols Therapeutics LLC · Immunology
IVIG-PEG is a polyethylene glycol-conjugated intravenous immunoglobulin that provides passive immune protection by delivering pooled human antibodies with extended half-life. - Delayed administration of convalescent plasma · UMC Utrecht · Immunology/Infectious Disease
Convalescent plasma transfers antibodies and immune factors from recovered patients to provide passive immunotherapy against infectious disease. - Octagam (IVIG) · Oslo University Hospital · Immunology
Octagam is an intravenous immunoglobulin (IVIG) that provides passive immunity by supplying pooled antibodies from multiple donors to modulate immune responses and neutralize pathogens. - LIV-GAMMA SN Inj.10% · SK Plasma Co., Ltd. · Immunology, Hematology
LIV-GAMMA SN is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by delivering pooled human antibodies to modulate immune responses. - IGIV-C 10% · Grifols Therapeutics LLC · Immunology
IGIV-C 10% is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by supplying pooled human antibodies to modulate immune responses. - Immunoglobulin perfusion · Centre Hospitalier Universitaire de Saint Etienne · Immunology
Immunoglobulin perfusion delivers immunoglobulins directly to affected tissues via regional perfusion to enhance local immune response and antibody concentration. - IGIV3I Grifols · Instituto Grifols, S.A. · Immunology
IGIV3I is an intravenous immunoglobulin (IVIG) product that provides passive immunity by delivering pooled human antibodies to modulate immune responses. - IgPro20 (high dose) · CSL Behring · Immunology
IgPro20 is a subcutaneous immunoglobulin replacement therapy that provides passive immunity by delivering polyclonal human immunoglobulins to treat primary immunodeficiency. - IGIV GAMMAGARD LIQUID/KIOVIG · Baxalta now part of Shire · Immunology
IGIV (intravenous immunoglobulin) provides passive immunity by supplying pooled human antibodies to replace or supplement deficient or dysfunctional immunoglobulin in patients with immune deficiencies or autoimmune conditions. - IVIG infusion · McMaster University · Immunology / Hematology
IVIG (intravenous immunoglobulin) provides passive immunity by delivering pooled antibodies from multiple donors to modulate immune responses and neutralize pathogens or autoimmune mediators. - BP-SCIG 20% · Biopharma Plasma LLC · Immunology
BP-SCIG 20% is a subcutaneous immunoglobulin replacement therapy that provides passive immunity by delivering immunoglobulin G (IgG) antibodies to patients with primary immunodeficiency. - Civacir® 10% · Biotest Pharmaceuticals Corporation · Immunology / Infectious Disease
Civacir is a hepatitis C immunoglobulin (HCV-IG) that provides passive immunity by supplying antibodies against hepatitis C virus to prevent reinfection in transplant recipients. - IRX-101 · iRenix Medical, Inc. · Immunology
IRX-101 is an intravenous immunoglobulin (IVIG) formulation designed to modulate immune responses and reduce inflammation. - Convalescent Plasma · Hackensack Meridian Health · Immunology/Infectious Disease
Convalescent plasma transfers antibodies and immune factors from recovered patients to provide passive immunotherapy against infectious disease. - Ig NextGen 10% · CSL Limited · Immunology
Ig NextGen 10% is an intravenous immunoglobulin (IVIG) product that provides passive immunity by delivering pooled human antibodies to modulate immune function and replace deficient immunoglobulins. - Intravenous ImmuneGlobulin · University Health Network, Toronto · Immunology
Intravenous immunoglobulin (IVIG) provides passive immunity by delivering pooled antibodies from multiple donors to neutralize pathogens and modulate immune responses. - KamRAB - HRIG · Kamada, Ltd. · Infectious Disease / Immunology
KamRAB is a human rabies immunoglobulin (HRIG) that provides passive immunity by supplying antibodies against rabies virus. - Kedrion IVIG 10% · Kedrion S.p.A. · Immunology
Kedrion IVIG 10% is an intravenous immunoglobulin preparation that provides passive immunity by supplying pooled human antibodies to modulate immune responses and neutralize pathogens. - IntragamP · CSL Limited · Immunology
IntragamP is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by delivering pooled human antibodies to modulate immune responses. - Panzyga, 10% Intravenous Solution · Octapharma · Immunology
Panzyga is an intravenous immunoglobulin (IVIG) that provides passive immunity by supplying pooled human antibodies to modulate immune responses and reduce inflammation. - IGSC 20% infusion · Takeda · Immunology
IGSC 20% is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by delivering pooled human antibodies to modulate immune function and replace deficient immunoglobulins. - IgG Next Generation (BT595) · Biotest · Immunology
BT595 is a next-generation intravenous immunoglobulin (IVIG) product designed to provide passive immunity through polyclonal IgG antibodies with enhanced manufacturing and purification processes. - Placebo and IVIG · The Hospital for Sick Children · Immunology
IVIG (intravenous immunoglobulin) provides passive immunization by supplying pooled antibodies from healthy donors to modulate immune function, while placebo serves as the control comparator. - IgM-enriched IVIG · Fakultas Kedokteran Universitas Indonesia · Immunology
IgM-enriched IVIG provides passive immunotherapy by supplying immunoglobulin M antibodies to enhance immune response and modulate inflammatory pathways. - IGIV3I Grifols 10% · Grifols Biologicals, LLC · Immunology
IGIV3I is an intravenous immunoglobulin (IVIG) product that provides passive immunity by delivering pooled human antibodies to modulate immune responses and provide immunoprotection. - IgY · Mukoviszidose Institut gGmbH · Respiratory / Infectious Disease
IgY is a polyclonal immunoglobulin Y (chicken antibody) therapeutic that targets and neutralizes Pseudomonas aeruginosa virulence factors and biofilm components in the respiratory tract. - PVRV and pERIG Favirab® · Sanofi Pasteur, a Sanofi Company · Infectious Disease / Virology
PVRV and pERIG Favirab® are rabies immunoglobulins that provide passive post-exposure prophylaxis by neutralizing rabies virus through direct antibody binding. - IgNextGen 10% · CSL Limited · Immunology; Hematology
IgNextGen 10% is an intravenous immunoglobulin (IVIG) product that provides passive immunity by delivering pooled human antibodies to modulate immune function and replace deficient immunoglobulins. - Gamunex Intravenous Immunoglobulin · National Institute of Mental Health (NIMH) · Immunology
Gamunex is an intravenous immunoglobulin (IVIG) that provides passive immunity by supplying pooled human antibodies to enhance immune function and modulate inflammatory responses. - Gammaplex 10 · Bio Products Laboratory · Immunology
Gammaplex 10 is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by delivering pooled human antibodies to modulate immune function and replace deficient immunoglobulins. - IgPro20 (low dose) · CSL Behring · Immunology
IgPro20 is a subcutaneous immunoglobulin replacement therapy that provides passive immunity by delivering polyclonal human immunoglobulins to patients with primary immunodeficiency. - Human immunoglobulin intravenous · Green Cross Corporation · Immunology / Infectious Disease / Hematology
Human immunoglobulin intravenous (IVIG) provides passive immunity by delivering pooled antibodies from multiple human donors to neutralize pathogens and modulate immune responses. - NewGam · Octapharma · Immunology
Provides passive immunity and immune modulation through polyspecific human immunoglobulins that interact with Fc receptors and complement components. - Human rabies immunoglobulins · Sanofi Pasteur, a Sanofi Company · Infectious Disease / Immunology
Human rabies immunoglobulins provide passive immunity by supplying antibodies that neutralize rabies virus and prevent its progression to the central nervous system. - IgNextGen 16% · CSL Limited · Immunology
IgNextGen 16% is an intravenous immunoglobulin (IVIG) product that provides passive immunization by delivering pooled human antibodies to modulate immune function and replace deficient immunoglobulins. - Rabies vaccines + Rabies immunoglobulins · Novartis · Infectious Disease / Immunology
Rabies vaccines stimulate immune response against rabies virus, while rabies immunoglobulins provide immediate passive immunity through pre-formed antibodies. - RI-002 · ADMA Biologics, Inc. · Immunology
RI-002 is an intravenous immunoglobulin (IVIG) product that provides passive immunity by delivering polyclonal human antibodies to boost immune function.
Phase 2 pipeline (1)
- IV Gamunex 10% · The Center for Rheumatic Disease, Allergy, & Immunology · Immunology
Immunomodulation through the administration of intravenous immunoglobulin
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