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human histaglobulin
human histaglobulin is a Polyclonal immunoglobulin; antihistamine immunoglobulin Biologic drug developed by Hangzhou Grand Biologic Pharmaceutical, Inc.. It is currently FDA-approved for Allergic diseases and conditions, Urticaria, Allergic rhinitis.
Human histaglobulin is a polyclonal immunoglobulin preparation that modulates immune responses by providing passive immunization and stabilizing mast cells to reduce histamine release.
Human histaglobulin is a polyclonal immunoglobulin preparation that modulates immune responses by providing passive immunization and stabilizing mast cells to reduce histamine release. Used for Allergic diseases and conditions, Urticaria, Allergic rhinitis.
At a glance
| Generic name | human histaglobulin |
|---|---|
| Sponsor | Hangzhou Grand Biologic Pharmaceutical, Inc. |
| Drug class | Polyclonal immunoglobulin; antihistamine immunoglobulin |
| Target | Histamine and mast cell stabilization |
| Modality | Biologic |
| Therapeutic area | Immunology; Allergy |
| Phase | FDA-approved |
Mechanism of action
This drug is derived from pooled human plasma and contains antibodies against histamine and other mediators of allergic and inflammatory responses. It works by binding histamine and other inflammatory mediators, reducing their bioavailability, and stabilizing mast cells to prevent degranulation. This mechanism helps attenuate allergic and inflammatory reactions in conditions characterized by excessive histamine release.
Approved indications
- Allergic diseases and conditions
- Urticaria
- Allergic rhinitis
Common side effects
- Injection site reactions
- Headache
- Fever
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- human histaglobulin CI brief — competitive landscape report
- human histaglobulin updates RSS · CI watch RSS
- Hangzhou Grand Biologic Pharmaceutical, Inc. portfolio CI
Frequently asked questions about human histaglobulin
What is human histaglobulin?
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Related
- Drug class: All Polyclonal immunoglobulin; antihistamine immunoglobulin drugs
- Target: All drugs targeting Histamine and mast cell stabilization
- Manufacturer: Hangzhou Grand Biologic Pharmaceutical, Inc. — full pipeline
- Therapeutic area: All drugs in Immunology; Allergy
- Indication: Drugs for Allergic diseases and conditions
- Indication: Drugs for Urticaria
- Indication: Drugs for Allergic rhinitis
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing