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IntragamP

CSL Limited · Phase 3 active Small molecule

IntragamP is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by delivering pooled human antibodies to modulate immune responses.

IntragamP is an intravenous immunoglobulin (IVIG) preparation that provides passive immunity by delivering pooled human antibodies to modulate immune responses. Used for Primary immunodeficiency disorders, Autoimmune and inflammatory conditions.

At a glance

Generic nameIntragamP
SponsorCSL Limited
Drug classIntravenous immunoglobulin (IVIG)
TargetFc receptors, complement system, pathogenic antibodies
ModalitySmall molecule
Therapeutic areaImmunology
PhasePhase 3

Mechanism of action

As an IVIG product, IntragamP contains polyvalent immunoglobulins (primarily IgG) derived from pooled human plasma. It works through multiple mechanisms including neutralization of pathogenic antibodies, blockade of Fc receptors on immune cells, and modulation of complement activation and cytokine production. This results in immunomodulatory and anti-inflammatory effects useful in treating primary immunodeficiencies and autoimmune conditions.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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