H2 receptor antagonist

This page covers all H2 receptor antagonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Multidrug and toxin extrusion protein 1, Acetylcholinesterase, Histamine H2 receptor, Histamine H2 receptor.

Targets

Multidrug and toxin extrusion protein 1, Acetylcholinesterase, Histamine H2 receptor · Histamine H2 receptor

Marketed (3)

• Zantac · GSK (originally Glaxo) · Cardiovascular
• Famotidine (FAM) · Bristol-Myers Squibb · Gastroenterology
  Famotidine is a histamine H2-receptor antagonist that reduces gastric acid secretion by blocking histamine-mediated stimulation of parietal cells in the stomach.
• Drug: cimetidine · University of Maryland, Baltimore · Gastroenterology
  Cimetidine blocks histamine H2 receptors on gastric parietal cells to reduce stomach acid production.

Phase 3 pipeline (2)

• Cimetidine IV · Bausch Health Americas, Inc. · Gastroenterology
  Cimetidine is a histamine H2-receptor antagonist that reduces gastric acid secretion by blocking histamine-mediated stimulation of parietal cells.
• H2 Receptor Antagonist · Merck Sharp & Dohme LLC · Gastroenterology
  H2 receptor antagonists block histamine H2 receptors on gastric parietal cells to reduce stomach acid secretion.