Fluoroquinolone

This page covers all Fluoroquinolone drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting DNA gyrase and topoisomerase IV, DNA gyrase, DNA-dependent RNA polymerase, DNA gyrase, topoisomerase IV.

Targets

DNA gyrase and topoisomerase IV · DNA gyrase · DNA-dependent RNA polymerase, DNA gyrase, topoisomerase IV · DNA gyrase, topoisomerase IV

Marketed (4)

• Gatifloxacin 0.3% · Innovative Medical · Infectious Disease
• Cipro · Alk Abello
  Ciprofloxacin interferes with bacterial DNA gyrase, inhibiting DNA synthesis.
• Levofloxacin Ophthalmic · National University of Malaysia · Infectious Disease
  Levofloxacin ophthalmic is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, leading to bacterial cell death.
• Experimental: Active "I-Reconstruction" Therapy · International Association Psychosomatics And Health Therapy · Infectious Disease
  Ofloxacin ophthalmic solution is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, leading to bacterial cell death.

Phase 3 pipeline (2)

• rifapentine and moxifloxacin · Centers for Disease Control and Prevention · Infectious Diseases
  Rifapentine is a bactericidal antibiotic that inhibits DNA-dependent RNA polymerase, while moxifloxacin is a bactericidal antibiotic that inhibits DNA gyrase and topoisomerase IV.
• Moxifloxacin or Levofloxacin · UMC Utrecht · Infectious Diseases
  Moxifloxacin and Levofloxacin are broad-spectrum antibiotics that inhibit DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication.

Phase 2 pipeline (1)

• Levofloxacin 500 · Dr. Reddy's Laboratories Limited · Infectious Disease
  Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and repair.