Combination antibiotic

This page covers all Combination antibiotic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Bacterial 30S ribosome (minocycline); microbial DNA/RNA (metronidazole), Penicillin-binding proteins, 30S ribosomal subunit.

Targets

Bacterial 30S ribosome (minocycline); microbial DNA/RNA (metronidazole) · Penicillin-binding proteins, 30S ribosomal subunit

Marketed (1)

• Minocycline,Metronidazole · Shanghai Jiao Tong University School of Medicine · Infectious Disease
  This combination of minocycline (a tetracycline antibiotic) and metronidazole (a nitroimidazole antimicrobial) works synergistically to inhibit bacterial protein synthesis and DNA/RNA metabolism, respectively, providing broad-spectrum antimicrobial coverage.

Phase 3 pipeline (1)

• procaine penicillin, gentamicin, amoxicillin · Aga Khan University · Infectious diseases
  Procaine penicillin is a combination antibiotic that works by inhibiting bacterial cell wall synthesis and protein synthesis, while gentamicin is an aminoglycoside antibiotic that works by inhibiting protein synthesis, and amoxicillin is a beta-lactam antibiotic that works by inhibiting cell wall synthesis.