What are Collagenase enzyme drugs?

Collagenase enzyme drugs are pharmacologic agents that share a common mechanism (typically targeting Collagen I and III). 6 are currently marketed, with 0 more in clinical development.

What are the marketed Collagenase enzyme drugs?

Marketed Collagenase enzyme drugs include CCH administration, Control - Crossover to CCH, Collagenase Clostridium Histolyticum-Aaes, XIAFLEX, Injectable clostridial collagenase, Qwo.

Collagenase enzyme

6 marketed

This page covers all Collagenase enzyme drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Collagen I and III, Collagen (types I and III), Collagen types I and III.

Targets

Collagen I and III · Collagen (types I and III) · Collagen types I and III · Collagen (types I, II, III, IV, V, VI, VII)

Marketed (6)

CCH administration · Charitable Union for the Research and Education of Peyronie's Disease · Urology / Sexual Health
CCH (collagenase clostridium histolyticum) is an injectable enzyme that breaks down collagen in penile plaques, reducing curvature and improving erectile function in Peyronie's disease.
Control - Crossover to CCH · Charitable Union for the Research and Education of Peyronie's Disease · Urology / Sexual Medicine
This is a crossover study comparing a control arm to collagenase clostridium histolyticum (CCH) treatment for Peyronie's disease.
Collagenase Clostridium Histolyticum-Aaes · Luxurgery · Dermatology / Rheumatology
Collagenase Clostridium Histolyticum-Aaes is a bacterial enzyme that directly breaks down collagen in connective tissue, allowing mechanical disruption of fibrotic structures.
XIAFLEX · Hospital for Special Surgery, New York · Orthopedics / Rheumatology
Xiaflex is a collagenase that breaks down collagen in fibrotic tissue, allowing mechanical manipulation to improve joint mobility and function.
Injectable clostridial collagenase · Indiana Hand to Shoulder Center · Orthopedics / Hand Surgery
Injectable clostridial collagenase breaks down collagen in fibrotic tissue, allowing mechanical disruption of contractures and scar tissue.
Qwo · DMR Research, PLLC · Dermatology
Qwo is a mixture of collagenase clostridium histolyticum enzymes that enzymatically breaks down collagen in subcutaneous tissue to reduce the appearance of cellulite.