Local anesthetic; Class IB antiarrhythmic agent

This page covers all Local anesthetic; Class IB antiarrhythmic agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Voltage-gated sodium channels, Cardiac voltage-gated sodium channel (Nav1.5).

Targets

Voltage-gated sodium channels · Cardiac voltage-gated sodium channel (Nav1.5)

Marketed (1)

• IV lignocaine bolus and infusion · University of Auckland, New Zealand · Cardiovascular; Anesthesia
  Lignocaine (lidocaine) is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.

Phase 3 pipeline (1)

• Oral Capsule Mexiletine (IR) · Lupin Ltd. · Cardiovascular
  Mexiletine is a class IB antiarrhythmic agent that blocks cardiac sodium channels to suppress abnormal electrical activity and restore normal heart rhythm.

Patent intelligence

• class ib antiarrhythmic agent patent landscape — aggregated cliff calendar, attackable patents, originator estates