Antiviral
This page covers all Antiviral drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting SARS-CoV-2 main protease (Mpro), M protein, Thymidylate synthase, Dihydrofolate reductase.
Targets
SARS-CoV-2 main protease (Mpro) · M protein · Thymidylate synthase, Dihydrofolate reductase · NS5B polymerase · Human papillomavirus (HPV) E6 and E7 proteins · SARS-CoV-2 spike protein · SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) · Hepatitis B virus
Marketed (3)
- ibuzatrelvir · Pfizer · Infectious Disease
- group M · Ain Shams University · Infectious Diseases
This drug works by inhibiting the activity of the M protein. - VA · JW Pharmaceutical · Infectious Diseases
Valacyclovir is an antiviral medication that works by inhibiting viral DNA synthesis.
Phase 3 pipeline (8)
- Trifluridine/Tipracil · Australasian Gastro-Intestinal Trials Group · Oncology
Trifluridine/Tipracil is an antiviral drug that works by inhibiting thymidylate synthase and dihydrofolate reductase. - Pegylated Interferon/ribavirin · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Hepatology
Pegylated interferon works by stimulating the body's immune system to fight viral infections, while ribavirin is an antiviral medication that inhibits viral replication. - CITUS Dry Syrup · SamA Pharmaceutical Co., Ltd · Infectious Diseases
CITUS Dry Syrup is a medication that works by inhibiting the action of a specific enzyme. - Ribavirin, PEG-Intron · Weill Medical College of Cornell University · Infectious Diseases
Ribavirin is an antiviral medication that works by inhibiting viral RNA synthesis, while PEG-Intron is an interferon that stimulates the body's immune response to fight viral infections. - Peginterferon alpha-2a + Ribavirin · Casa Sollievo della Sofferenza IRCCS · Infectious Diseases
Peginterferon alpha-2a is a recombinant form of interferon-alpha-2a, which is a protein that helps to stimulate the body's immune response to viral infections, while Ribavirin is an antiviral medication that inhibits viral replication. - sinecatechins 10% topical ointment · Hospital Universitari Vall d'Hebron Research Institute · Dermatology
Sinecatechins 10% topical ointment works by inhibiting the replication of human papillomavirus (HPV) in the skin. - KOCITAF · Professor Francois Venter · Infectious Disease
KOCITAF is a small molecule drug that targets the SARS-CoV-2 virus. - VYD222 (pemivibart) · Invivyd, Inc. · Infectious Disease
VYD222 (pemivibart) is an investigational antiviral medication that works by inhibiting the replication of SARS-CoV-2.
Phase 2 pipeline (1)
- ARB-001467 · Arbutus Biopharma Corporation · Infectious Diseases
ARB-001467 is an investigational drug that targets the hepatitis B virus.