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VA
Valacyclovir is an antiviral medication that works by inhibiting viral DNA synthesis.
Valacyclovir is an antiviral medication that works by inhibiting viral DNA synthesis. Used for Herpes zoster (shingles), Herpes simplex virus infections (genital and cutaneous), Varicella (chickenpox).
At a glance
| Generic name | VA |
|---|---|
| Also known as | C2101, Venetoclax+Azacitidine |
| Sponsor | JW Pharmaceutical |
| Drug class | Antiviral |
| Modality | Small molecule |
| Therapeutic area | Infectious Diseases |
| Phase | FDA-approved |
Mechanism of action
Valacyclovir is a prodrug of acyclovir, which is converted into its active form inside the body. It selectively inhibits viral DNA synthesis by competing with deoxyguanosine triphosphate for viral DNA polymerase, thereby preventing viral replication.
Approved indications
- Herpes zoster (shingles)
- Herpes simplex virus infections (genital and cutaneous)
- Varicella (chickenpox)
Common side effects
- Nausea
- Headache
- Diarrhea
- Abdominal pain
- Vomiting
Key clinical trials
- Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma (PHASE3)
- MRI Quantification of Pulmonary Fibrosis in Scleroderma Patients (NA)
- Biomarkers of Reaction To HIIT Exercise (NA)
- VAG Versus Standard Chemotherapy With FLT3 Inhibitor in Adult Patients With FLT3-Mutated AML (PHASE3)
- Pain Management Teams Using Whole Health to Optimize Function and Safety in Veterans: The TEAMWORK Trial (NA)
- Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation (NA)
- Brief Versus Standard Cognitive Behavioral Therapy for Insomnia in Veterans (NA)
- Together in Recovery With Veterans Through Employment (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |