Anticonvulsant
This page covers all Anticonvulsant drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Voltage-gated calcium channels, α2δ subunit of voltage-gated calcium channels, Nicotinic acetylcholine receptor.
Targets
Voltage-gated calcium channels · α2δ subunit of voltage-gated calcium channels · Nicotinic acetylcholine receptor · Voltage-dependent sodium channels · Voltage-dependent sodium channels, GABA_A receptor · Voltage-gated sodium channels · Voltage-sensitive sodium channels
Marketed (3)
- Neither Pregabalin nor Gabapentin · CAMC Health System · Pain
It works by binding to voltage-gated calcium channels in the nervous system, reducing the release of pain-causing chemicals. - Pregabalin 25 MG · Ajou University School of Medicine · Neuroscience
- Magnesium Sulfate In Dextrose 5% In Plastic Container · Pfizer Inc.
Magnesium Sulfate blocks neuromuscular transmission and decreases acetylcholine levels, leading to vasodilation and a depressant effect on the central nervous system.
Phase 3 pipeline (3)
- topiramate, phenytoin · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · Neurology
Topiramate is an anticonvulsant that works by blocking voltage-dependent sodium channels, stabilizing neuronal membranes, and reducing the release of excitatory neurotransmitters. - topiramate, propranolol · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · Neurology
Topiramate is an anticonvulsant that blocks voltage-dependent sodium channels and enhances the activity of GABA at the GABA_A receptor. - valproic acid (VPA) · Hospital Universitari de Bellvitge · Neurology
Valproic acid acts as a sodium channel blocker and inhibits the release of excitatory neurotransmitters.
Phase 2 pipeline (1)
- Lamotrigine tablets · GlaxoSmithKline · Neurology
Blocks voltage-sensitive sodium channels