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Zyprexa® (OLANZapine 5MG) — Competitive Intelligence Brief
phase 3
atypical antipsychotic
D2 receptor, 5-HT2A receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
Zyprexa® (OLANZapine 5MG) (Zyprexa® (OLANZapine 5MG)) — CR-CSSS Champlain-Charles-Le Moyne. Zyprexa works by blocking the action of dopamine and serotonin in the brain, which helps to reduce symptoms of psychosis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Zyprexa® (OLANZapine 5MG) TARGET | Zyprexa® (OLANZapine 5MG) | CR-CSSS Champlain-Charles-Le Moyne | phase 3 | atypical antipsychotic | D2 receptor, 5-HT2A receptor | |
| Risperidone, oral tablets | Risperidone, oral tablets | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | phase 3 | atypical antipsychotic | D2 receptor, 5-HT2A receptor | |
| Olanzapine, risperidone | Olanzapine, risperidone | AstraZeneca | phase 3 | atypical antipsychotic | D2 receptor, 5-HT2A receptor | |
| Risperdal Consta (drug) | Risperdal Consta (drug) | University of Illinois at Chicago | phase 3 | Atypical antipsychotic | D2 receptor, 5-HT2A receptor | |
| Risperidone and placebo comparator | Risperidone and placebo comparator | University of Alabama at Birmingham | phase 3 | atypical antipsychotic | D2 receptor, 5-HT2A receptor | |
| Rapid Acting Intramuscular Olanzapine | Rapid Acting Intramuscular Olanzapine | Eli Lilly and Company | phase 3 | atypical antipsychotic | D2 receptor, 5-HT2A receptor | |
| bifeprunox, olanzapine | bifeprunox, olanzapine | Wyeth is now a wholly owned subsidiary of Pfizer | phase 3 | Atypical antipsychotic | D2 receptor, 5-HT2A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (atypical antipsychotic class)
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 2 drugs in this class
- AstraZeneca · 2 drugs in this class
- Eli Lilly and Company · 1 drug in this class
- University of Alabama at Birmingham · 1 drug in this class
- Qilu Pharmaceutical Co., Ltd. · 1 drug in this class
- Sumitomo Pharma Co., Ltd. · 1 drug in this class
- CR-CSSS Champlain-Charles-Le Moyne · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Zyprexa® (OLANZapine 5MG) — Competitive Intelligence Brief. https://druglandscape.com/ci/zyprexa-olanzapine-5mg. Accessed 2026-05-17.
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