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ZL-1109 (VRDN-003) — Competitive Intelligence Brief
phase 3
PD-1 inhibitor
PD-1
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
ZL-1109 (VRDN-003) (ZL-1109 (VRDN-003)) — Zai Lab (Shanghai) Co., Ltd.. ZL-1109 (VRDN-003) is a small molecule targeting the PD-1 receptor.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ZL-1109 (VRDN-003) TARGET | ZL-1109 (VRDN-003) | Zai Lab (Shanghai) Co., Ltd. | phase 3 | PD-1 inhibitor | PD-1 | |
| Penpulimab kcqx | PENPULIMAB | Akeso Biopharma | marketed | Pd-1 | 2025-01-01 | |
| Tevimbra | TISLELIZUMAB | Beigene | marketed | Programmed Death Receptor-1 Blocking Antibody [EPC] | Pd-1 | 2025-01-01 |
| Loqtorzi | TORIPALIMAB | Coherus Biosciences Inc | marketed | Programmed Death Receptor-1 Blocking Antibody [EPC] | Pd-1 | 2024-01-01 |
| Unloxcyt | COSIBELIMAB | Checkpoint Therapeutics Inc | marketed | Programmed Death Ligand-1 Blocker [EPC] | Pd-1 | 2024-01-01 |
| Jemperli | DOSTARLIMAB | GSK | marketed | Programmed Death Receptor-1 Blocking Antibody [EPC] | PD-1 | 2021-01-01 |
| Libtayo | CEMIPLIMAB | Regeneron Pharmaceuticals | marketed | PD-1 | 2018-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (PD-1 inhibitor class)
- Sun Yat-sen University · 11 drugs in this class
- Bristol-Myers Squibb · 9 drugs in this class
- Addpharma Inc. · 7 drugs in this class
- Merck Sharp & Dohme LLC · 5 drugs in this class
- Shanghai Henlius Biotech · 5 drugs in this class
- Innovent Biologics (Suzhou) Co. Ltd. · 5 drugs in this class
- Pfizer · 4 drugs in this class
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · 4 drugs in this class
- Amgen · 3 drugs in this class
- Daewoong Pharmaceutical Co. LTD. · 3 drugs in this class
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- ZL-1109 (VRDN-003) CI watch — RSS
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Cite this brief
Drug Landscape (2026). ZL-1109 (VRDN-003) — Competitive Intelligence Brief. https://druglandscape.com/ci/zl-1109-vrdn-003. Accessed 2026-05-17.
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