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YM060 — Competitive Intelligence Brief

YM060 (YM060) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: kappa opioid receptor antagonist. Area: Pain.

phase 3 kappa opioid receptor antagonist kappa opioid receptor Pain Small molecule Live · refreshed every 30 min

Target snapshot

YM060 (YM060) — Astellas Pharma Inc. YM060 is a selective and potent kappa opioid receptor antagonist.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
YM060 TARGET YM060 Astellas Pharma Inc phase 3 kappa opioid receptor antagonist kappa opioid receptor
BENZHYDROCODONE BENZHYDROCODONE marketed Opioid analgesic combination; full mu-opioid agonist with non-opioid analgesic Mu-opioid receptors (primary); delta and kappa opioid receptors (secondary); central nervous system pain pathways 2018-01-01
NALBUPHINE HYDROCHLORIDE NALBUPHINE HYDROCHLORIDE marketed kappa opioid receptors, mu opioid receptors 1979-01-01
XR-NTX 380 mg, intramuscular injection XR-NTX 380 mg, intramuscular injection University of Pennsylvania marketed Opioid receptor antagonist Mu opioid receptor (primary); delta and kappa opioid receptors
standard opioid prescribing standard opioid prescribing Walter Reed National Military Medical Center marketed Opioid analgesic Mu opioid receptor, delta opioid receptor, kappa opioid receptor
Motrin and narcotic Motrin and narcotic Cape Fear Valley Health System marketed NSAID + opioid analgesic combination COX-1/COX-2 (ibuprofen); mu, delta, and kappa opioid receptors (narcotic component)
Individualized oral morphine Individualized oral morphine Children's Hospital of Fudan University marketed Opioid analgesic Mu opioid receptor (primary), delta opioid receptor, kappa opioid receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (kappa opioid receptor antagonist class)

  1. Astellas Pharma Inc · 1 drug in this class
  2. QRxPharma Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). YM060 — Competitive Intelligence Brief. https://druglandscape.com/ci/ym060. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing