Last reviewed · How we verify
standard opioid prescribing
Opioids bind to opioid receptors in the central and peripheral nervous system to reduce pain perception and emotional response to pain.
Opioids bind to opioid receptors in the central and peripheral nervous system to reduce pain perception and emotional response to pain. Used for Moderate to severe acute pain, Moderate to severe chronic pain, Cancer pain.
At a glance
| Generic name | standard opioid prescribing |
|---|---|
| Sponsor | Walter Reed National Military Medical Center |
| Drug class | Opioid analgesic |
| Target | Mu opioid receptor, delta opioid receptor, kappa opioid receptor |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | FDA-approved |
Mechanism of action
Opioids are mu, delta, and kappa receptor agonists that modulate pain signaling pathways in the brain and spinal cord. By activating these receptors, they decrease the transmission and perception of pain signals and alter the emotional experience of pain. Standard prescribing refers to evidence-based dosing and administration protocols for various opioid medications used in clinical practice.
Approved indications
- Moderate to severe acute pain
- Moderate to severe chronic pain
- Cancer pain
- Postoperative pain
Common side effects
- Constipation
- Nausea
- Drowsiness
- Dizziness
- Respiratory depression
- Dependence and addiction
- Pruritus
Key clinical trials
- MedSMA℞T Mobile ED (NA)
- ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
- Safe Prescription of Opioids in Primary Care (NA)
- Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in High-risk Users (PHASE4)
- Opioid-Sparing Joint Replacement (PHASE3)
- Opioid Use Post-Discharge After Ambulatory Distal Arm Surgery (NA)
- Postoperative Pain Management Following Robotic Assisted Sacrocolpopexy (NA)
- A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- standard opioid prescribing CI brief — competitive landscape report
- standard opioid prescribing updates RSS · CI watch RSS
- Walter Reed National Military Medical Center portfolio CI