Last reviewed · How we verify
WHO-recommended SOC Itraconazole — Competitive Intelligence Brief
phase 3
Triazole antifungal
Lanosterol 14α-demethylase
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
WHO-recommended SOC Itraconazole (WHO-recommended SOC Itraconazole) — University of Minnesota. Itraconazole inhibits the synthesis of ergosterol, an essential component of fungal cell membranes.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| WHO-recommended SOC Itraconazole TARGET | WHO-recommended SOC Itraconazole | University of Minnesota | phase 3 | Triazole antifungal | Lanosterol 14α-demethylase | |
| Loceryl NL 12 weeks | Loceryl NL 12 weeks | Galderma R&D | marketed | Allylamine antifungal | Lanosterol 14α-demethylase (CYP51) | |
| Topical Clotrimazole cream | Topical Clotrimazole cream | Hayat Abad Medical Complex, Peshawar | marketed | Imidazole antifungal | Fungal lanosterol 14α-demethylase (CYP51) | |
| Clotrimazole 1% | Clotrimazole 1% | Jinnah Postgraduate Medical Centre | marketed | Imidazole antifungal | Fungal cytochrome P450 (lanosterol 14α-demethylase) | |
| Bifonazole Cream | Bifonazole Cream | Galderma R&D | marketed | Imidazole antifungal | Lanosterol 14α-demethylase (CYP51) | |
| Topical ketoconazole 2% cream | Topical ketoconazole 2% cream | PAEC General Hospital, Islamabad | marketed | Imidazole antifungal | Fungal cytochrome P450 (CYP51 / lanosterol 14α-demethylase) | |
| Voriconazole low dose | Voriconazole low dose | Manjunath Prakash Pai | marketed | Triazole antifungal | Lanosterol 14α-demethylase (CYP51) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Triazole antifungal class)
- University of Maryland, Baltimore · 3 drugs in this class
- Manjunath Prakash Pai · 2 drugs in this class
- Pfizer · 2 drugs in this class
- Janssen Pharmaceutical K.K. · 1 drug in this class
- Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- Seoul National University Hospital · 1 drug in this class
- University of California, San Francisco · 1 drug in this class
- University of Minnesota · 1 drug in this class
- Bayer · 1 drug in this class
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Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- WHO-recommended SOC Itraconazole CI watch — RSS
- WHO-recommended SOC Itraconazole CI watch — Atom
- WHO-recommended SOC Itraconazole CI watch — JSON
- WHO-recommended SOC Itraconazole alone — RSS
- Whole Triazole antifungal class — RSS
Cite this brief
Drug Landscape (2026). WHO-recommended SOC Itraconazole — Competitive Intelligence Brief. https://druglandscape.com/ci/who-recommended-soc-itraconazole. Accessed 2026-05-18.
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