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valproate microgranules — Competitive Intelligence Brief
marketed
Anticonvulsant / Mood stabilizer
Histone deacetylase; GABA metabolism
Neurology / Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
valproate microgranules (valproate microgranules) — Sanofi. Valproate inhibits histone deacetylase and enhances GABAergic neurotransmission, leading to increased GABA levels and neuronal stabilization.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| valproate microgranules TARGET | valproate microgranules | Sanofi | marketed | Anticonvulsant / Mood stabilizer | Histone deacetylase; GABA metabolism | |
| Divalproex (DV) | Divalproex (DV) | Weill Medical College of Cornell University | marketed | Histone deacetylase inhibitor; anticonvulsant; mood stabilizer | Histone deacetylase; GABA metabolism; sodium and calcium channels | |
| Divalproex Sodium (Depakote) | Divalproex Sodium (Depakote) | National Institute on Drug Abuse (NIDA) | phase 3 | Histone deacetylase inhibitor; anticonvulsant; mood stabilizer | Histone deacetylase; GABA metabolism; sodium channels | |
| Brand lamotrigine | Brand lamotrigine | University of Maryland, Baltimore | marketed | Anticonvulsant / Mood stabilizer | Voltage-gated sodium channels; glutamate release inhibition | |
| Low dose lamotrigine | Low dose lamotrigine | Mario Negri Institute for Pharmacological Research | marketed | Anticonvulsant / Mood stabilizer | Voltage-gated sodium channels; glutamate release modulation | |
| Lamictal TM | Lamictal TM | Central Mental Clinic for Outpatients of Baku City | marketed | Anticonvulsant / Mood stabilizer | Voltage-gated sodium channels; glutamate release inhibition | |
| Divalproex (DIV) ER | Divalproex (DIV) ER | The University of Texas Health Science Center at San Antonio | marketed | Anticonvulsant / Mood stabilizer | GABA synthesis enhancement; histone deacetylase inhibition |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anticonvulsant / Mood stabilizer class)
- University of Maryland, Baltimore · 4 drugs in this class
- Sanofi · 2 drugs in this class
- University of Cincinnati · 2 drugs in this class
- Mario Negri Institute for Pharmacological Research · 1 drug in this class
- Central Mental Clinic for Outpatients of Baku City · 1 drug in this class
- The University of Texas Health Science Center at San Antonio · 1 drug in this class
- University Hospitals Cleveland Medical Center · 1 drug in this class
- Dhaka Medical College · 1 drug in this class
- Korea Otsuka Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). valproate microgranules — Competitive Intelligence Brief. https://druglandscape.com/ci/valproate-microgranules. Accessed 2026-05-13.
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