Topical Lidocaine 4% Cream — Competitive Intelligence Brief

Topical Lidocaine 4% Cream (Topical Lidocaine 4% Cream) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia/Pain Management.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia/Pain Management Small molecule

Target snapshot

Topical Lidocaine 4% Cream (Topical Lidocaine 4% Cream) — Children's Hospital of Philadelphia. Lidocaine blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses to produce local anesthesia.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Topical Lidocaine 4% Cream TARGET	Topical Lidocaine 4% Cream	Children's Hospital of Philadelphia	marketed	Local anesthetic	Voltage-gated sodium channels
Liposomal Bupivacaine	Liposomal Bupivacaine	Wake Forest University Health Sciences	marketed	Local anesthetic	Voltage-gated sodium channels
Active bupivacaine 0.375% PENG block	Active bupivacaine 0.375% PENG block	University of California, San Diego	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine %2 ampoule	Lidocaine %2 ampoule	Kaohsiung Medical University Chung-Ho Memorial Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Non-buffered Anesthetic	Non-buffered Anesthetic	University Hospitals Cleveland Medical Center	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine HCl 0.8% in D5W	Lidocaine HCl 0.8% in D5W	Vanderbilt University Medical Center	marketed	Local anesthetic / Antiarrhythmic (Class IB)	Voltage-gated sodium channels
Liposomal bupivacaine left injection	Liposomal bupivacaine left injection	Prisma Health-Upstate	marketed	Local anesthetic (amide)	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class