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Tivdak — Competitive Intelligence Brief
marketed
Antibody-drug conjugate
Tissue factor
Oncology
Monoclonal antibody
Live · refreshed every 30 min
Target snapshot
Tivdak (tisotumab-vedotin) — SEAGEN. Tisotumab vedotin is a tissue factor (TF)-directed antibody drug conjugate that targets and disrupts microtubule networks in cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Tivdak TARGET | tisotumab-vedotin | SEAGEN | marketed | Antibody-drug conjugate | Tissue factor | 2021-01-01 |
| Tisotumab Vedotin | tivdak | SEAGEN | marketed | Antibody-Drug Conjugate (ADC) | Tissue factor | 2021-01-01 |
| Hympavzi | Marstacimab-Hncq | Pfizer Inc. | marketed | Tissue Factor Pathway Inhibitor (TFPI) Antagonist | Tissue Factor Pathway Inhibitor (TFPI) Kunitz domain 2 (K2) | |
| Eptacog alfa (NovoSeven) | Eptacog alfa (NovoSeven) | Novo Nordisk A/S | marketed | Recombinant coagulation factor | Tissue factor (TF) / Factor X | |
| BIVV009 | BIVV009 | Bioverativ, a Sanofi company | phase 3 | TFPI inhibitor monoclonal antibody | Tissue Factor Pathway Inhibitor (TFPI) | |
| BT524 | BT524 | Biotest | phase 3 | Monoclonal antibody (anti-TFPI) | Tissue Factor Pathway Inhibitor (TFPI) | |
| BT595 | BT595 | Biotest | phase 3 | Monoclonal antibody (anti-TFPI) | Tissue Factor Pathway Inhibitor (TFPI) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antibody-drug conjugate class)
- Amgen · 1 drug in this class
- Hellenic Cooperative Oncology Group · 1 drug in this class
- Roche · 1 drug in this class
- SEAGEN · 1 drug in this class
- Sanofi · 1 drug in this class
- Sung-Soo Park · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Tivdak — Competitive Intelligence Brief. https://druglandscape.com/ci/tisotumab-vedotin. Accessed 2026-05-16.
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