Who are Ticagrelor first's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): bivalirudin + clopidogrel + aspirin, Clopidogrel, cilostazol, Clopidogrel only, aspirin + clopidogrel + celecoxib, prasugrel/bivalirudin, aspirin and/or clopidogrel.

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Last reviewed 2026-05-14 · How we verify

Ticagrelor first — Competitive Intelligence Brief

Ticagrelor first (Ticagrelor first) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: P2Y12 receptor antagonist. Area: Cardiovascular.

marketed P2Y12 receptor antagonist P2Y12 Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Ticagrelor first (Ticagrelor first) — Ping-Yen Liu. Ticagrelor is a direct-acting P2Y12 receptor antagonist that inhibits platelet aggregation by blocking adenosine diphosphate (ADP) signaling.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Ticagrelor first TARGET	Ticagrelor first	Ping-Yen Liu	marketed	P2Y12 receptor antagonist	P2Y12
bivalirudin + clopidogrel + aspirin	bivalirudin + clopidogrel + aspirin	Centre Hospitalier de PAU	marketed	Anticoagulant + antiplatelet combination	Thrombin (Factor IIa), P2Y12 receptor, cyclooxygenase
Clopidogrel, cilostazol	Clopidogrel, cilostazol	Kyunghee University Medical Center	marketed	Antiplatelet agent combination	P2Y12 receptor (clopidogrel); phosphodiesterase-3 (cilostazol)
Clopidogrel only	Clopidogrel only	Seung-Jung Park	marketed	P2Y12 receptor antagonist / Thienopyridine antiplatelet agent	P2Y12 receptor
aspirin + clopidogrel + celecoxib	aspirin + clopidogrel + celecoxib	Seoul National University Hospital	marketed	Antiplatelet agent combination with NSAID	COX-1, P2Y12 receptor, COX-2
prasugrel/bivalirudin	prasugrel/bivalirudin	I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio	marketed	Antiplatelet agent + Direct thrombin inhibitor combination	P2Y12 receptor (prasugrel); Thrombin (bivalirudin)
aspirin and/or clopidogrel	aspirin and/or clopidogrel	Asan Medical Center	marketed	Antiplatelet agent	COX (aspirin); P2Y12 receptor (clopidogrel)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (P2Y12 receptor antagonist class)

First Affiliated Hospital of Harbin Medical University · 4 drugs in this class
Fu Wai Hospital, Beijing, China · 1 drug in this class
Ping-Yen Liu · 1 drug in this class
Samsung Medical Center · 1 drug in this class
St. Antonius Hospital · 1 drug in this class
University of Florida · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ticagrelor first — Competitive Intelligence Brief. https://druglandscape.com/ci/ticagrelor-first. Accessed 2026-05-14.

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