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Talzenna — Competitive Intelligence Brief

Talzenna (talazoparib-tosylate) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Poly(ADP-Ribose) Polymerase Inhibitor. Area: Oncology.

marketed Poly(ADP-Ribose) Polymerase Inhibitor PARP1, PARP2 Oncology Live · refreshed every 30 min

Target snapshot

Talzenna (talazoparib-tosylate) — Pfizer. Talazoparib inhibits PARP enzymes, causing DNA damage and cell death in cancer cells with DNA repair defects.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Talzenna TARGET talazoparib-tosylate Pfizer marketed Poly(ADP-Ribose) Polymerase Inhibitor PARP1, PARP2 2018-01-01
Pharmacokinetics, Dosage of Niraparib Pharmacokinetics, Dosage of Niraparib Hospices Civils de Lyon marketed PARP inhibitor PARP1, PARP2
Olaparib Treatment D Olaparib Treatment D AstraZeneca marketed PARP inhibitor PARP1, PARP2
Active comparator: Niraparib Active comparator: Niraparib Tesaro, Inc. phase 3 PARP inhibitor PARP1, PARP2
Olaparib tablet Olaparib tablet Fondazione Ricerca Traslazionale phase 3 PARP inhibitor PARP1, PARP2
Saruparib (AZD5305) Saruparib (AZD5305) AstraZeneca phase 3 PARP inhibitor PARP1, PARP2
Active Comparator: Olaparib tablets Active Comparator: Olaparib tablets AstraZeneca phase 3 PARP inhibitor PARP1, PARP2

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (Poly(ADP-Ribose) Polymerase Inhibitor class)

  1. Pfizer · 2 drugs in this class
  2. GSK · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Talzenna — Competitive Intelligence Brief. https://druglandscape.com/ci/talazoparib-tosylate. Accessed 2026-05-16.

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