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Std-dose iv MgSO4 — Competitive Intelligence Brief
phase 3
Anticonvulsant, Vasodilator
Voltage-gated calcium channels
Cardiovascular, Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Std-dose iv MgSO4 (Std-dose iv MgSO4) — Hamad Medical Corporation. Magnesium sulfate acts as an anticonvulsant and vasodilator by inhibiting neuronal excitability and promoting blood vessel dilation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Std-dose iv MgSO4 TARGET | Std-dose iv MgSO4 | Hamad Medical Corporation | phase 3 | Anticonvulsant, Vasodilator | Voltage-gated calcium channels | |
| Losartan/amlodipine or losartan/hydrochlorothiazide | Losartan/amlodipine or losartan/hydrochlorothiazide | Yokohama City University Medical Center | marketed | Angiotensin II receptor blocker combination (ARB + calcium channel blocker or ARB + thiazide diuretic) | Angiotensin II type 1 receptor (AT1R); L-type voltage-gated calcium channels (amlodipine) or sodium-chloride cotransporter (hydrochlorothiazide) | |
| Lyrica (pregabalin) | Lyrica (pregabalin) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | marketed | Gabapentinoid; anticonvulsant; anxiolytic | Alpha-2-delta subunit of voltage-gated calcium channels | |
| Pregabalin 25 MG | Pregabalin 25 MG | Ajou University School of Medicine | marketed | Anticonvulsant | α2δ subunit of voltage-gated calcium channels | |
| gabapentin + tramadol | gabapentin + tramadol | Southwest Hospital, China | marketed | Analgesic combination (anticonvulsant + opioid) | Voltage-gated calcium channels (Cav2.1, Cav2.2); μ-opioid receptor; serotonin and norepinephrine transporters | |
| Lercanidipine/enalapril fixed combination | Lercanidipine/enalapril fixed combination | Meir Medical Center | marketed | Calcium channel blocker / ACE inhibitor combination | L-type voltage-gated calcium channels; Angiotensin-converting enzyme (ACE) | |
| Standard dose gabapentin | Standard dose gabapentin | Mario Negri Institute for Pharmacological Research | marketed | Anticonvulsant; gabapentinoid | Alpha-2-delta-1 subunit of voltage-gated calcium channels |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anticonvulsant, Vasodilator class)
- Hamad Medical Corporation · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Std-dose iv MgSO4 — Competitive Intelligence Brief. https://druglandscape.com/ci/std-dose-iv-mgso4. Accessed 2026-05-15.
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