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SP + amodiaquine — Competitive Intelligence Brief

SP + amodiaquine (SP + amodiaquine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimalarial. Area: Infectious Diseases.

phase 3 Antimalarial Dihydropteroate synthase, Dihydrofolate reductase Infectious Diseases Small molecule Live · refreshed every 30 min

Target snapshot

SP + amodiaquine (SP + amodiaquine) — London School of Hygiene and Tropical Medicine. Sulfadoxine and pyrimethamine work by inhibiting dihydropteroate synthase and dihydrofolate reductase, respectively, disrupting folic acid synthesis in Plasmodium parasites.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
SP + amodiaquine TARGET SP + amodiaquine London School of Hygiene and Tropical Medicine phase 3 Antimalarial Dihydropteroate synthase, Dihydrofolate reductase
Sulfadoxine pyrimethamine (SP) Sulfadoxine pyrimethamine (SP) Menzies School of Health Research phase 3 Antibiotic Dihydropteroate synthase, Dihydrofolate reductase
Sulphadoxine-Pyrimethamine+ Amodiaquine+ Azithromycin Sulphadoxine-Pyrimethamine+ Amodiaquine+ Azithromycin London School of Hygiene and Tropical Medicine phase 3 Antimalarial Dihydropteroate synthase, Dihydrofolate reductase, Heme detoxification pathway
Coartem ARTEMETHER marketed Antimalarial [EPC] 2009-01-01
Coartem LUMEFANTRINE Novartis marketed Antimalarial [EPC] Potassium voltage-gated channel subfamily H member 2 2009-01-01
Qualaquin QUININE Sun Pharm Industries marketed Antimalarial Sodium channel alpha subunits; brain (Types I, II, III) 2005-01-01
Malarone PROGUANIL GSK marketed Antimalarial [EPC] 2000-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimalarial class)

  1. London School of Hygiene and Tropical Medicine · 6 drugs in this class
  2. Sanofi · 3 drugs in this class
  3. Epicentre · 2 drugs in this class
  4. University of Oxford · 2 drugs in this class
  5. · 2 drugs in this class
  6. Frantz Viral Therapeutics, LLC · 1 drug in this class
  7. Assistance Publique - Hôpitaux de Paris · 1 drug in this class
  8. Institut de Recherche pour le Developpement · 1 drug in this class
  9. Centre de Recherche Médicale de Lambaréné · 1 drug in this class
  10. GlaxoSmithKline · 1 drug in this class

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Cite this brief

Drug Landscape (2026). SP + amodiaquine — Competitive Intelligence Brief. https://druglandscape.com/ci/sp-amodiaquine. Accessed 2026-05-17.

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