Last reviewed · How we verify
Qualaquin (QUININE)
At a glance
| Generic name | QUININE |
|---|---|
| Sponsor | Sun Pharm Industries |
| Drug class | Antimalarial |
| Target | Sodium channel alpha subunits; brain (Types I, II, III) |
| Modality | Small molecule |
| Therapeutic area | Rare Disease |
| Phase | FDA-approved |
| First approval | 2005 |
Approved indications
- Chloroquine Resistant Plasmodium Falciparum Malaria
- Falciparum malaria
Common side effects
- Headache
- Nausea
- Vasodilation and sweating
- Tinnitus
- Hearing impairment
- Vertigo or dizziness
- Blurred vision
- Disturbance in color perception
- Vomiting
- Diarrhea
- Abdominal pain
- Deafness
Serious adverse events
- Agranulocytosis
- Thrombocytopenia
- Disseminated intravascular coagulation
- Hemolytic anemia
- Thrombotic thrombocytopenic purpura
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Ventricular fibrillation
- Renal failure
- Cardiac arrest
Drug interactions
- High Risk QT Prolonging Agents
- P-glycoprotein Substrates
- abarelix
- apomorphine
- chloroquine
- chlorpromazine
- clarithromycin
- dasatinib
- domperidone
- erythromycin
- grepafloxacin
- haloperidol
Key clinical trials
- Safety, Tolerability and Symptomatic Efficacy of the ROCK-Inhibitor Fasudil in Patients With Parkinson's Disease (PHASE2)
- Validation of Aspiration Markers in Intubated Patients (PHASE1)
- Safety of Antimalarials in the FIRst trimEster (PHASE3)
- Omega-3, Nigella Sativa, Indian Costus, Quinine, Anise Seed, Deglycyrrhizinated Licorice, Artemisinin, Febrifugine on Immunity of Patients With (COVID-19) (PHASE2,PHASE3)
- Taste Physiology in Obese Volunteers Before and After Bariatric Surgery (NA)
- Effects of Intragastric Quinine, Alone or Combined With L-leucine, on Postprandial Glycaemic Control (NA)
- Effects of Intragastric Quinine, Alone or Combined With L-isoleucine, on Postprandial Glycaemic Control (NA)
- Effect of Quinine Hydrochloride in Overweight Population on Food Intake, Hunger and Gut Peptide Release (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |