Sevorane (sevoflurane, Abbott) — Competitive Intelligence Brief

Sevorane (sevoflurane, Abbott) (Sevorane (sevoflurane, Abbott)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Volatile anesthetic. Area: Anesthesiology.

marketed Volatile anesthetic GABA-A receptor, NMDA glutamate receptor Anesthesiology Small molecule

Target snapshot

Sevorane (sevoflurane, Abbott) (Sevorane (sevoflurane, Abbott)) — Medical University of Gdansk. Sevoflurane is a volatile anesthetic that depresses the central nervous system by enhancing inhibitory GABA neurotransmission and inhibiting excitatory glutamate signaling.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Sevorane (sevoflurane, Abbott) TARGET	Sevorane (sevoflurane, Abbott)	Medical University of Gdansk	marketed	Volatile anesthetic	GABA-A receptor, NMDA glutamate receptor
Sevoflurane inhalant product	Sevoflurane inhalant product	Sunnybrook Health Sciences Centre	marketed	Volatile inhalational anesthetic	GABA-A receptor, NMDA glutamate receptor
Sevoflurane or Propofol	Sevoflurane or Propofol	University Health Network, Toronto	marketed	General anesthetic	GABA-A receptor, NMDA glutamate receptor
Inhaled sedation with sevoflurane	Inhaled sedation with sevoflurane	University Hospital, Clermont-Ferrand	phase 3	Volatile anesthetic	GABA-A receptor, NMDA glutamate receptor
General sevoflurane anaesthesia	General sevoflurane anaesthesia	KK Women's and Children's Hospital	phase 3	Volatile anesthetic agent	GABA-A receptor, NMDA glutamate receptor
Sevoflurane, Isoflurane, Desflurane	Sevoflurane, Isoflurane, Desflurane	University Hospital, Basel, Switzerland	marketed	Volatile anesthetic	GABA-A receptor, NMDA receptor
Sevoflurane (Preconditioning)	Sevoflurane (Preconditioning)	University of Zurich	marketed	Volatile anesthetic with cardioprotective preconditioning properties	Mitochondrial ATP-sensitive potassium channels (mitoKATP); protein kinase C; endothelial nitric oxide synthase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Volatile anesthetic class)

1. Medical University of Gdansk · 2 drugs in this class
2. Assistance Publique - Hôpitaux de Paris · 1 drug in this class
3. Federal University of São Paulo · 1 drug in this class
4. King's College Hospital NHS Trust · 1 drug in this class
5. London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · 1 drug in this class
6. The Cleveland Clinic · 1 drug in this class
7. University Hospital, Basel, Switzerland · 1 drug in this class
8. Asan Medical Center · 1 drug in this class
9. University Hospital, Clermont-Ferrand · 1 drug in this class