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Self-Administered Nitrous Oxide — Competitive Intelligence Brief
marketed
Inhalational anesthetic and analgesic
NMDA receptor antagonist
Anesthesia and Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
Self-Administered Nitrous Oxide (Self-Administered Nitrous Oxide) — Beth Israel Deaconess Medical Center. Nitrous oxide acts as a dissociative anesthetic and analgesic by antagonizing N-methyl-D-aspartate (NMDA) receptors in the central nervous system.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Self-Administered Nitrous Oxide TARGET | Self-Administered Nitrous Oxide | Beth Israel Deaconess Medical Center | marketed | Inhalational anesthetic and analgesic | NMDA receptor antagonist | |
| Sulfate, Magnesium | Sulfate, Magnesium | Assistance Publique - Hôpitaux de Paris | marketed | Electrolyte supplement; anticonvulsant; smooth muscle relaxant | NMDA receptor antagonist; calcium channel blocker | |
| Dextromethorphan Oral Solution | Dextromethorphan Oral Solution | Helsinki University Central Hospital | marketed | Non-opioid antitussive | NMDA receptor antagonist; sigma-1 receptor | |
| Nitrous Oxide/Oxygen | Nitrous Oxide/Oxygen | Nationwide Children's Hospital | marketed | Inhalational anesthetic and analgesic gas | NMDA receptor antagonist; GABAergic potentiator | |
| Magnesium Sulfate Infusion | Magnesium Sulfate Infusion | Ondokuz Mayıs University | marketed | Electrolyte supplement / anticonvulsant / tocolytic agent | NMDA receptor antagonist; calcium channel modulator | |
| Oxygen/nitrous oxide equimolar mix | Oxygen/nitrous oxide equimolar mix | Hospital St. Joseph, Marseille, France | marketed | Inhalational anesthetic/analgesic gas mixture | NMDA receptor antagonist; endogenous opioid system modulation | |
| IV Magnesium Sulfate | IV Magnesium Sulfate | University Hospitals Cleveland Medical Center | marketed | Electrolyte supplement / anticonvulsant | NMDA receptor antagonist; calcium channel blocker (non-selective) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Inhalational anesthetic and analgesic class)
- Beth Israel Deaconess Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Self-Administered Nitrous Oxide — Competitive Intelligence Brief. https://druglandscape.com/ci/self-administered-nitrous-oxide. Accessed 2026-05-14.
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