Who are Selective serotonin re-uptake inhibitor's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lexapro, Prozac, Sertraline [Zoloft], SSRI (SEROPLEX ou ZOLOFT), oral escitalopram, SSRI antidepressants.

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Last reviewed 2026-05-16 · How we verify

Selective serotonin re-uptake inhibitor — Competitive Intelligence Brief

Selective serotonin re-uptake inhibitor (Selective serotonin re-uptake inhibitor) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Selective serotonin reuptake inhibitor (SSRI). Area: Psychiatry / Neurology.

marketed Selective serotonin reuptake inhibitor (SSRI) Serotonin transporter (SERT) Psychiatry / Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Selective serotonin re-uptake inhibitor (Selective serotonin re-uptake inhibitor) — New Valley University. SSRIs block the reuptake of serotonin at the presynaptic neuron, increasing serotonin concentration in the synaptic cleft.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Selective serotonin re-uptake inhibitor TARGET	Selective serotonin re-uptake inhibitor	New Valley University	marketed	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)
Lexapro	escitalopram	Generic (originally Lundbeck/Forest)	marketed	Selective Serotonin Reuptake Inhibitor (SSRI)	Serotonin (5-HT) reuptake transporter	2002-08-14
Prozac	fluoxetine	Eli Lilly and Company	marketed	Selective Serotonin Reuptake Inhibitor (SSRI)	Serotonin reuptake transporter	1987-12-29
Sertraline [Zoloft]	Sertraline [Zoloft]	Johns Hopkins University	marketed	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)
SSRI (SEROPLEX ou ZOLOFT)	SSRI (SEROPLEX ou ZOLOFT)	Centre Hospitalier Universitaire Dijon	marketed	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)
oral escitalopram	oral escitalopram	NYU Langone Health	marketed	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)
SSRI antidepressants	SSRI antidepressants	Nanjing Medical University	marketed	Selective serotonin reuptake inhibitor (SSRI)	Serotonin transporter (SERT)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Selective serotonin reuptake inhibitor (SSRI) class)

University of Texas Southwestern Medical Center · 3 drugs in this class
Johns Hopkins University · 2 drugs in this class
GlaxoSmithKline · 2 drugs in this class
Daiichi Sankyo Co., Ltd. · 1 drug in this class
Guangdong Provincial People's Hospital · 1 drug in this class
Janssen Research & Development, LLC · 1 drug in this class
Medical University of Vienna · 1 drug in this class
Massachusetts General Hospital · 1 drug in this class
Fundació Sant Joan de Déu · 1 drug in this class
Centre Hospitalier Universitaire Dijon · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Selective serotonin re-uptake inhibitor — Competitive Intelligence Brief. https://druglandscape.com/ci/selective-serotonin-re-uptake-inhibitor. Accessed 2026-05-16.

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