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Rescue Medication: Olopatadine ophthalmic drops — Competitive Intelligence Brief
phase 3
Selective H1-receptor antagonist and mast cell stabilizer
H1 histamine receptor
Ophthalmology / Allergy
Small molecule
Live · refreshed every 30 min
Target snapshot
Rescue Medication: Olopatadine ophthalmic drops (Rescue Medication: Olopatadine ophthalmic drops) — ALK-Abelló A/S. Olopatadine is a selective H1-receptor antagonist and mast cell stabilizer that blocks histamine-mediated allergic responses in the eye.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Rescue Medication: Olopatadine ophthalmic drops TARGET | Rescue Medication: Olopatadine ophthalmic drops | ALK-Abelló A/S | phase 3 | Selective H1-receptor antagonist and mast cell stabilizer | H1 histamine receptor | |
| olopatadine (OLO) | olopatadine (OLO) | University of Chicago | marketed | Selective H1-receptor antagonist / mast cell stabilizer | H1 histamine receptor | |
| Morphine-Promethazine | Morphine-Promethazine | Tel-Aviv Sourasky Medical Center | marketed | Opioid analgesic combination | Mu-opioid receptor (morphine); H1 histamine receptor (promethazine) | |
| Fluticasone furoate and fexofenadine | Fluticasone furoate and fexofenadine | GlaxoSmithKline | marketed | Intranasal corticosteroid and antihistamine combination | Glucocorticoid receptor (fluticasone furoate); H1 histamine receptor (fexofenadine) | |
| Hydroxyzine HCL | Hydroxyzine HCL | National Cancer Institute (NCI) | marketed | First-generation H1 antihistamine | H1 histamine receptor | |
| Diphenhydramine 5% | Diphenhydramine 5% | Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology | marketed | H1 receptor antagonist (first-generation antihistamine) | H1 histamine receptor | |
| fexofenadine HCl | fexofenadine HCl | Sanofi | marketed | Second-generation H1-receptor antagonist (non-sedating antihistamine) | H1 histamine receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Selective H1-receptor antagonist and mast cell stabilizer class)
- ALK-Abelló A/S · 1 drug in this class
- Bausch & Lomb Incorporated · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Rescue Medication: Olopatadine ophthalmic drops — Competitive Intelligence Brief. https://druglandscape.com/ci/rescue-medication-olopatadine-ophthalmic-drops. Accessed 2026-05-16.
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