Who are REFRESH OPTIVE UD's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Systane Complete Preservative-Free, preservative-free 0.15% HA, Meticel Ofteno®, Systane Ultra Preservative Free, Sodium hyaluronate 0.15%, PEG- 400 based artificial tear.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

REFRESH OPTIVE UD — Competitive Intelligence Brief

REFRESH OPTIVE UD (REFRESH OPTIVE UD) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Artificial tear / Ocular lubricant. Area: Ophthalmology.

phase 3 Artificial tear / Ocular lubricant Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

REFRESH OPTIVE UD (REFRESH OPTIVE UD) — AbbVie. REFRESH OPTIVE UD is an artificial tear solution that lubricates and protects the ocular surface to relieve dry eye symptoms.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class
REFRESH OPTIVE UD TARGET	REFRESH OPTIVE UD	AbbVie	phase 3	Artificial tear / Ocular lubricant
Systane Complete Preservative-Free	Systane Complete Preservative-Free	University of Waterloo	marketed	Artificial tear / Ocular lubricant
preservative-free 0.15% HA	preservative-free 0.15% HA	Chang Gung Memorial Hospital	marketed	Artificial tear / ocular lubricant
Meticel Ofteno®	Meticel Ofteno®	Laboratorios Sophia S.A de C.V.	marketed	Artificial tear / Ocular lubricant
Systane Ultra Preservative Free	Systane Ultra Preservative Free	Laboratorios Sophia S.A de C.V.	marketed	Artificial tear / Ocular lubricant
Sodium hyaluronate 0.15%	Sodium hyaluronate 0.15%	Laboratorios Sophia S.A de C.V.	marketed	Artificial tear / Ocular lubricant
PEG- 400 based artificial tear	PEG- 400 based artificial tear	Bp Consulting, Inc	marketed	Artificial tear / Ocular lubricant

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Artificial tear / Ocular lubricant class)

Laboratorios Sophia S.A de C.V. · 7 drugs in this class
Allergan · 3 drugs in this class
University of Waterloo · 2 drugs in this class
University of California, Berkeley · 2 drugs in this class
Bp Consulting, Inc · 1 drug in this class
Chong Kun Dang Pharmaceutical · 1 drug in this class
Clinica Oftamologica Zona Sul · 1 drug in this class
Fundação Altino Ventura · 1 drug in this class
Medical University of South Carolina · 1 drug in this class
Ocuwize LTD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). REFRESH OPTIVE UD — Competitive Intelligence Brief. https://druglandscape.com/ci/refresh-optive-ud. Accessed 2026-05-13.

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