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Reduced dose of DOAC — Competitive Intelligence Brief

Reduced dose of DOAC (Reduced dose of DOAC) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Direct Oral Anticoagulant (DOAC). Area: Cardiovascular.

phase 3 Direct Oral Anticoagulant (DOAC) Factor Xa or Factor IIa (thrombin) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Reduced dose of DOAC (Reduced dose of DOAC) — University Hospital, Brest. A reduced dose of a direct oral anticoagulant (DOAC) inhibits specific coagulation factors to prevent thrombus formation while minimizing bleeding risk through dose optimization.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Reduced dose of DOAC TARGET Reduced dose of DOAC University Hospital, Brest phase 3 Direct Oral Anticoagulant (DOAC) Factor Xa or Factor IIa (thrombin)
Pradaxa dabigatran etexilate Generic (originally Boehringer Ingelheim) marketed Direct oral anticoagulant (DOAC) — direct thrombin inhibitor Multidrug and toxin extrusion protein 1, Multidrug and toxin extrusion protein 2, Ribosyldihydronicotinamide dehydrogenase [quinone] 2010-10-19
Rivaroxaban, Dabigatran Rivaroxaban, Dabigatran University Hospital, Grenoble marketed Direct oral anticoagulant (DOAC) Factor Xa (rivaroxaban); Thrombin/Factor IIa (dabigatran)
Dabigatran; Rivaroxaban Dabigatran; Rivaroxaban University Hospital, Grenoble marketed Direct oral anticoagulant (DOAC) Dabigatran: Factor IIa (thrombin); Rivaroxaban: Factor Xa
Rivaroxaban, dabigatran, apixaban, or edoxaban Rivaroxaban, dabigatran, apixaban, or edoxaban Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec marketed Direct oral anticoagulant (DOAC) Factor Xa (rivaroxaban, apixaban, edoxaban) or Thrombin (dabigatran)
Full dose of DOAC Full dose of DOAC University Hospital, Brest phase 3 Direct oral anticoagulant (DOAC) Factor Xa or Factor IIa (thrombin)
Direct oral anticoagulant Direct oral anticoagulant Centre Hospitalier Universitaire de Nīmes phase 3 Direct oral anticoagulant (DOAC)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Direct Oral Anticoagulant (DOAC) class)

  1. University Hospital, Brest · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Reduced dose of DOAC — Competitive Intelligence Brief. https://druglandscape.com/ci/reduced-dose-of-doac. Accessed 2026-05-17.

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