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Ramipril (ACE-inhibitor) — Competitive Intelligence Brief
marketed
ACE inhibitor
Angiotensin-converting enzyme (ACE)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Ramipril (ACE-inhibitor) (Ramipril (ACE-inhibitor)) — National Heart Institute, Egypt. Ramipril inhibits angiotensin-converting enzyme (ACE), reducing the conversion of angiotensin I to angiotensin II and thereby lowering blood pressure and reducing cardiac workload.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ramipril (ACE-inhibitor) TARGET | Ramipril (ACE-inhibitor) | National Heart Institute, Egypt | marketed | ACE inhibitor | Angiotensin-converting enzyme (ACE) | |
| Vasotec | enalapril | Merck & Co. | marketed | ACE inhibitor | Angiotensin-converting enzyme, Angiotensin-converting enzyme | 1985-12-24 |
| Calcium Channel Blockers, ACE-Inhibitor | Calcium Channel Blockers, ACE-Inhibitor | University of Aarhus | marketed | Combination antihypertensive (calcium channel blocker + ACE inhibitor) | L-type calcium channels; Angiotensin-converting enzyme (ACE) | |
| ACE Inhibitors and Diuretics | ACE Inhibitors and Diuretics | The University of Texas Health Science Center, Houston | marketed | ACE inhibitor + diuretic combination | Angiotensin-converting enzyme (ACE); various diuretic targets depending on class (e.g., loop of Henle, distal convoluted tubule) | |
| captopril, Losartan (drug) | captopril, Losartan (drug) | National Taiwan University Hospital | marketed | ACE inhibitor and angiotensin II receptor antagonist combination | ACE enzyme and AT1 receptor | |
| RASi plus carvedilol | RASi plus carvedilol | Federal University of Minas Gerais | marketed | ACE inhibitor or ARB combined with non-selective beta-blocker | Angiotensin II receptor / ACE enzyme; beta-1 and beta-2 adrenergic receptors; alpha-1 adrenergic receptor | |
| Perindopril + amlodipine + if necessary, hydrochlorothiazide | Perindopril + amlodipine + if necessary, hydrochlorothiazide | Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company | marketed | ACE inhibitor + calcium channel blocker + thiazide diuretic combination | Angiotensin-converting enzyme (ACE), L-type calcium channels, sodium-chloride cotransporter |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (ACE inhibitor class)
- Boryung Pharmaceutical Co., Ltd · 5 drugs in this class
- Bioprojet · 2 drugs in this class
- Ain Shams University · 2 drugs in this class
- Ahn-Gook Pharmaceuticals Co.,Ltd · 1 drug in this class
- Beijing Tide Pharmaceutical Co., Ltd · 1 drug in this class
- Children's Hospital of Fudan University · 1 drug in this class
- Ache Laboratorios Farmaceuticos S.A. · 1 drug in this class
- Daewon Pharmaceutical Co., Ltd. · 1 drug in this class
- Ethicare GmbH · 1 drug in this class
- Ace Cells Lab Limited · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ramipril (ACE-inhibitor) — Competitive Intelligence Brief. https://druglandscape.com/ci/ramipril-ace-inhibitor. Accessed 2026-05-16.
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