Who are Isocain's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lotronex, Anzemet, Aureotan, Lidocain, Lignocaine, Namenda.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Isocain — Competitive Intelligence Brief

Isocain (PROCAINE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Amide Local Anesthetic [EPC]. Area: Pain.

marketed Amide Local Anesthetic [EPC] 5-hydroxytryptamine receptor 3A Pain Small molecule Live · refreshed every 30 min

Target snapshot

Isocain (PROCAINE) — Pfizer.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Isocain TARGET	PROCAINE	Pfizer	marketed	Amide Local Anesthetic [EPC]	5-hydroxytryptamine receptor 3A	1954-01-01
Lotronex	ALOSETRON	Legacy Pharma	marketed	Serotonin-3 Receptor Antagonist	5-hydroxytryptamine receptor 3A	2000-01-01
Anzemet	DOLASETRON	Validus Pharms	marketed	Serotonin-3 Receptor Antagonist	5-hydroxytryptamine receptor 3A	1997-01-01
Aureotan	aurothioglucose		marketed	aurothioglucose	5-hydroxytryptamine receptor 3A
Lidocain	Lidocain	Bayer	marketed		5-hydroxytryptamine receptor 3A, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, Sodium channel protein type 10 subunit alpha
Lignocaine	Lignocaine	University of Malaya	marketed		5-hydroxytryptamine receptor 3A, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, Sodium channel protein type 10 subunit alpha
Namenda	Namenda	Inova Health Care Services	marketed		Solute carrier family 22 member 1, 5-hydroxytryptamine receptor 3A, Acetylcholinesterase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Amide Local Anesthetic [EPC] class)

· 1 drug in this class
Dentsply International · 1 drug in this class
Pfizer · 1 drug in this class
Reedfresh Co., LTD · 1 drug in this class
Rigshospitalet, Denmark · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Isocain — Competitive Intelligence Brief. https://druglandscape.com/ci/procaine. Accessed 2026-05-14.

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